Identification of a small compound that specifically inhibits Zika virus in vitro and in vivo by targeting the NS2B-NS3 protease.
Sign Up to like & getrecommendations! Published in 2022 at "Antiviral research"
DOI: 10.1016/j.antiviral.2022.105255
Abstract: Zika virus (ZIKV) has rapid become a global threat, but no ZIKV-specific vaccines or drugs are currently available. In this study, inhibitors of ZIKV NS2B-NS3 protease were screened from a library containing 4,452 compound fragments.… read more here.
Keywords: zika virus; small compound; ns2b ns3; compound ... See more keywords
Novel synaptic plasticity enhancer drug to augment functional recovery with rehabilitation
Sign Up to like & getrecommendations! Published in 2019 at "Current Opinion in Neurology"
DOI: 10.1097/wco.0000000000000748
Abstract: Purpose of review Stroke is a devastating illness which severely attenuates quality of life because of paralysis. Despite recent advances in therapies during acute phase such as thrombolytic therapy, clinical option to intervene the process… read more here.
Keywords: rehabilitation; small compound; recovery; functional recovery ... See more keywords