Patient‐derived in vitro skin models for investigation of small fiber pathology
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.50871
Abstract: To establish individually expandable primary fibroblast and keratinocyte cultures from 3‐mm skin punch biopsies for patient‐derived in vitro skin models to investigate of small fiber pathology. read more here.
Keywords: derived vitro; skin models; vitro skin; small fiber ... See more keywords
Long-term efficacy of immunoglobulins in small fiber neuropathy related to Sjögren’s syndrome
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DOI: 10.1007/s00415-020-10033-z
Abstract: The most common peripheral nervous system manifestations in Sjogren’s syndrome are small fiber sensory neuropathies (SFPN) and axonal sensorimotor polyneuropathies. Currently, treatment in small fiber neuropathy is mainly symptomatic and based on anti-depressors and anti-epileptics.… read more here.
Keywords: fiber neuropathy; term efficacy; long term; sjogren syndrome ... See more keywords
Small-fiber neuropathy definition, diagnosis, and treatment
Sign Up to like & getrecommendations! Published in 2019 at "Neurological Sciences"
DOI: 10.1007/s10072-019-03871-x
Abstract: In the last 30 years, improvement of diagnostic methods enabled routine evaluation of small A-delta and C nerve fibers impairment, which results with the clinical condition known as a small-fiber neuropathy (SFN). This syndrome develops as… read more here.
Keywords: fiber neuropathy; treatment; small fiber; definition diagnosis ... See more keywords
Pharmacotherapy for Small Fiber Neuropathy
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DOI: 10.1007/s11940-020-00652-2
Abstract: Small fiber neuropathy (SFN) is a condition that affects small nerve fibers leading to a variety of symptoms, including pain, discomfort, tingling, and sensory loss. The development of new drugs is commonly complicated by variable… read more here.
Keywords: pharmacotherapy small; fiber neuropathy; treatment; small fiber ... See more keywords
The histopathological evaluation of small fiber neuropathy in patients with vitamin B12 deficiency
Sign Up to like & getrecommendations! Published in 2017 at "Acta Neurologica Belgica"
DOI: 10.1007/s13760-017-0847-y
Abstract: Small fiber neuropathy (SFN), due to loss of A-delta and unmyelinated C fibers, is a cause of neuropathic pain. Although the patients with vitamin B12 deficiency are included in SFN studies in the literature, there… read more here.
Keywords: b12 deficiency; vitamin b12; small fiber; patients vitamin ... See more keywords
P2-03. An electrophysiological severity classification system for diabetic polyneuropathy and small fiber dysfunction
Sign Up to like & getrecommendations! Published in 2017 at "Clinical Neurophysiology"
DOI: 10.1016/j.clinph.2017.06.019
Abstract: We reported an electrophysiological severity classification for diabetic polyneuropathy (DPN) using a nerve conduction study (NCS). This new classification system combines of the amplitude and velocity of NCS and classifies DPN into five stages. Stage… read more here.
Keywords: electrophysiological severity; small fiber; stage stage; stage ... See more keywords
Neuropathic pain and symptoms of potential small-fiber neuropathy in fibromyalgic patients: a national on-line survey.
Sign Up to like & getrecommendations! Published in 2021 at "Joint bone spine"
DOI: 10.1016/j.jbspin.2021.105153
Abstract: OBJECTIVE recent studies have highlighted that about 50% of fibromyalgic patients has a neuropathy of small- and/or large-fibers which could partially explain the puzzling symptoms of fibromyalgia (FM). Our aim was to investigate the estimated… read more here.
Keywords: small fiber; pathology; pain symptoms; neuropathic pain ... See more keywords
A zebrafish model to study small-fiber neuropathy reveals a potential role for GDAP1.
Sign Up to like & getrecommendations! Published in 2019 at "Mitochondrion"
DOI: 10.1016/j.mito.2019.01.002
Abstract: Mutations in genes involved in mitochondrial dynamics (fusion and fission) have been implicated in many peripheral neuropathies. We hypothesized that defects in these genes could result in a phenotype resembling features of small-fiber neuropathy (SFN).… read more here.
Keywords: genes involved; fiber neuropathy; small fiber; involved mitochondrial ... See more keywords
Pyridoxine Toxicity Small Fiber Neuropathy With Dysautonomia: A Case Report.
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DOI: 10.1097/cnd.0000000000000172
Abstract: Pyridoxine (vitamin B6) toxicity is a well-known cause of primary sensory, length-dependent, axonal polyneuropathy. Although sensory symptoms predominate, autonomic symptoms have also been reported in some cases. To date, there is no objective evidence of… read more here.
Keywords: toxicity; small fiber; pyridoxine toxicity; case ... See more keywords
Efficacy of Electrical Stimulation on Nerve Fiber Growth in Small Fiber Neuropathy.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Neuromuscular Disease"
DOI: 10.1097/cnd.0000000000000280
Abstract: OBJECTIVES To define whether electrical nerve stimulation (ENS) therapy would promote intraepidermal nerve growth and nerve regeneration in patients with small fiber neuropathy (SFN). METHODS This was a prospective study conducted on 8 subjects with… read more here.
Keywords: nerve; growth; fiber neuropathy; ens therapy ... See more keywords
Immune-Mediated Small Fiber Neuropathy With Trisulfated Heparin Disaccharide, Fibroblast Growth Factor Receptor 3, or Plexin D1 Antibodies: Presentation and Treatment With Intravenous Immunoglobulin
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Neuromuscular Disease"
DOI: 10.1097/cnd.0000000000000423
Abstract: Abstract Objectives: Up to 50% of small fiber neuropathy (SFN) cases are idiopathic, but novel antibodies to Trisulfated Heparin Disaccharide (TS-HDS) and fibroblast growth factor receptor 3 (FGFR-3) have been implicated in half of these… read more here.
Keywords: fiber neuropathy; fiber; plexin; small fiber ... See more keywords