Articles with "small guide" as a keyword



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Development of a selection assay for small guide RNAs that drive efficient site-directed RNA editing

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Published in 2023 at "Nucleic Acids Research"

DOI: 10.1093/nar/gkad098

Abstract: Abstract A major challenge confronting the clinical application of site-directed RNA editing (SDRE) is the design of small guide RNAs (gRNAs) that can drive efficient editing. Although many gRNA designs have effectively recruited endogenous Adenosine… read more here.

Keywords: rna editing; site directed; selection assay; directed rna ... See more keywords