Computational design of small interfering RNAs and small hairpin RNAs to silence mutated P53 gene expressions
Sign Up to like & getrecommendations! Published in 2018 at "Informatics in Medicine Unlocked"
DOI: 10.1016/j.imu.2018.04.004
Abstract: Abstract RNA silencing is a novel gene regulatory mechanism that confines the transcript level by either preventing translation or by the initiation of particular RNA degradation. Small interfering RNAs are regularly represented as the exogenously… read more here.
Keywords: small interfering; p53 gene; small hairpin; interfering rnas ... See more keywords
Foliar Infiltration of Virus-Derived Small Hairpin RNAs Triggers the RNAi Mechanism against the Cucumber Mosaic Virus
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23094938
Abstract: Post-transcriptional gene silencing (PTGS) is an evolutionarily conserved plant defense mechanism against viruses. This paper aimed to evaluate a dsDNA construct (77 bp) as a template for in vitro production of virus-derived artificial small hairpin… read more here.
Keywords: rnai mechanism; virus derived; hairpin rnas; small hairpin ... See more keywords