Elucidation of Diverse Physico-Chemical Parameters in Mammalian Small Heat Shock Proteins: A Comprehensive Classification and Structural and Functional Exploration Using In Silico Approach
Sign Up to like & getrecommendations! Published in 2021 at "Applied Biochemistry and Biotechnology"
DOI: 10.1007/s12010-021-03497-w
Abstract: Small heat shock proteins (sHSPs), often known as molecular chaperones, are most prevalent in nature. Under certain stress-induced conditions, these sHSPs act as an ATP-independent variation and thus prevent the inactivation of various non-native substrate… read more here.
Keywords: heat shock; shock proteins; small heat; shsps ... See more keywords
Small Heat Shock Protein's Gene Expression Response to Iron Oxide Nanoparticles in the Brain.
Sign Up to like & getrecommendations! Published in 2021 at "Biological trace element research"
DOI: 10.1007/s12011-021-02761-8
Abstract: Small heat shock proteins (SHSPs) are conserved proteins that participate in many cellular functions like preventing protein aggregation and stress response. However, their role in responding to nanoparticles (NPs) has not yet been explained. We… read more here.
Keywords: small heat; response; nps; gene expression ... See more keywords
pH-dependent structural modulation is conserved in the human small heat shock protein HSBP1
Sign Up to like & getrecommendations! Published in 2017 at "Cell Stress and Chaperones"
DOI: 10.1007/s12192-017-0783-z
Abstract: The holdase activity and oligomeric propensity of human small heat shock proteins (sHSPs) are regulated by environmental factors. However, atomic-level details are lacking for the mechanisms by which stressors alter sHSP responses. We previously demonstrated… read more here.
Keywords: dependent structural; heat shock; small heat; human small ... See more keywords
The small heat shock proteins αB-crystallin (HSPB5) and Hsp27 (HSPB1) inhibit the intracellular aggregation of α-synuclein
Sign Up to like & getrecommendations! Published in 2017 at "Cell Stress and Chaperones"
DOI: 10.1007/s12192-017-0785-x
Abstract: Protein homeostasis, or proteostasis, is the process of maintaining the conformational and functional integrity of the proteome. Proteostasis is preserved in the face of stress by a complex network of cellular machinery, including the small… read more here.
Keywords: aggregation; syn aggregation; small heat; hsp27 ... See more keywords
Characterization and expression analysis of a new small heat shock protein Hsp20.4 from Eimeria tenella.
Sign Up to like & getrecommendations! Published in 2017 at "Experimental parasitology"
DOI: 10.1016/j.exppara.2017.10.006
Abstract: Small heat shock proteins (sHsps) are ubiquitous and diverse molecular chaperones. Found in almost all organisms, they regulate protein refolding and protect cells from stress. Until now, no sHsp has been characterized in Eimeria tenella.… read more here.
Keywords: protein; eimeria tenella; heat shock; small heat ... See more keywords
Involvement of small heat shock proteins (sHsps) in developmental stages of fall armyworm, Spodoptera frugiperda and its expression pattern under abiotic stress condition
Sign Up to like & getrecommendations! Published in 2021 at "Heliyon"
DOI: 10.1016/j.heliyon.2021.e06906
Abstract: Fall armyworm (FAW), Spodoptera frugiperda a recent invasive pest in India is reported to cause significant damage by feeding voraciously on maize and other economic crops from tropical to temperate provinces. It is becoming an… read more here.
Keywords: small heat; spodoptera frugiperda; stress; expression ... See more keywords
Genome-wide identification of small heat shock protein (HSP20) homologs in three cucurbit species and the expression profiles of CsHSP20s under several abiotic stresses.
Sign Up to like & getrecommendations! Published in 2021 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2021.08.222
Abstract: Small heat shock protein (HSP20) genes play important roles in biological processes of plants. In this study, a total of 47 CsHSP20 genes, 45 CmHSP20 genes, and 47 ClHSP20 genes were genome-wide identified by 'hmmsearch'… read more here.
Keywords: genome wide; small heat; heat shock; abiotic stresses ... See more keywords
Sequence analysis of Ricinus communis small heat-shock protein (sHSP) subfamily and its role in abiotic stress responses
Sign Up to like & getrecommendations! Published in 2020 at "Industrial Crops and Products"
DOI: 10.1016/j.indcrop.2020.112541
Abstract: Abstract Small heat shock proteins (sHSPs) possess major roles in plant defense mechanisms towards abiotic stresses. sHSPs act as molecular chaperones providing the necessary tools to sustain cellular homeostasis under adverse conditions. sHSP genes display… read more here.
Keywords: small heat; ricinus communis; shsp subfamily; heat shock ... See more keywords
Small heat shock protein CRYAB inhibits intestinal mucosal inflammatory responses and protects barrier integrity through suppressing IKKβ activity
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DOI: 10.1038/s41385-019-0198-5
Abstract: Alpha B-crystallin (CRYAB) is an important member of the small heat shock protein family, and plays a protective and therapeutic role in neurological inflammation. CRYAB expression was assessed in cultured HT29 and Caco-2 cells and… read more here.
Keywords: cryab; small heat; heat shock; expression ... See more keywords
O-GlcNAc modification of small heat shock proteins enhances their anti-amyloid chaperone activity
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DOI: 10.1038/s41557-021-00648-8
Abstract: A major role for the intracellular post-translational modification O-GlcNAc appears to be the inhibition of protein aggregation. Most of the previous studies in this area focused on O-GlcNAc modification of the amyloid-forming proteins themselves. Here… read more here.
Keywords: glcnac; glcnac modification; small heat; chemistry ... See more keywords
The small heat shock protein HSPB1 protects mice from sepsis
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DOI: 10.1038/s41598-018-30752-8
Abstract: In vitro studies have implicated the small heat shock protein HSPB1 in a range of physiological functions. However, its in vivo relevance is unclear as the phenotype of unstressed HSPB1−/− mice is unremarkable. To determine… read more here.
Keywords: sepsis; small heat; heat shock; mice ... See more keywords