Orelabrutinib in relapsed or refractory chronic lymphocytic leukemia/small lymphocytic lymphoma patients: Multi‐center, single‐arm, open‐label, phase 2 study
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DOI: 10.1002/ajh.26826
Abstract: Orelabrutinib is a novel, small molecule, selective irreversible Bruton's tyrosine kinase inhibitor. The aim of this study was to evaluate the efficacy and safety in patients with refractory or relapsed chronic lymphocytic leukemia (CLL)/small lymphocytic… read more here.
Keywords: lymphocytic leukemia; orelabrutinib; small lymphocytic; chronic lymphocytic ... See more keywords
The impacts of zanubrutinib on immune cells in patients with chronic lymphocytic leukemia/small lymphocytic lymphoma
Sign Up to like & getrecommendations! Published in 2019 at "Hematological Oncology"
DOI: 10.1002/hon.2667
Abstract: Ibrutinib, a first‐generation Bruton's tyrosine kinase (BTK) inhibitor, could improve immunity of relapsed or refractory (R/R) chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) patients. Whether zanubrutinib, a second‐generation selective BTK inhibitor, has similar effects as ibrutinib… read more here.
Keywords: cll; lymphocytic leukemia; treatment; small lymphocytic ... See more keywords
Blood and Guts: Diarrhea from Colonic Involvement in Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
Sign Up to like & getrecommendations! Published in 2018 at "Digestive Diseases and Sciences"
DOI: 10.1007/s10620-018-5264-4
Abstract: An 81-year-old male was initially evaluated in a local emergency department for a 6-week history of diarrhea. He had a history of coronary artery disease with remote coronary artery bypass graft and mechanical mitral valve… read more here.
Keywords: lymphocytic leukemia; small lymphocytic; blood; chronic lymphocytic ... See more keywords
Intracytoplasmic crystalline inclusions in peripheral blood lymphocytes in small lymphocytic lymphoma
Sign Up to like & getrecommendations! Published in 2022 at "British Journal of Haematology"
DOI: 10.1111/bjh.18380
Abstract: platelet count blood lymphocytes, amounts (images, Peripheral blood B lymphocytes, CD19, CD20 (weak), CD5, CD23, CD200 and CD43 CD10 surface and cytoplasmic An axillary lymph node bi-opsy showed a dense infiltrate of small lymphocytes with… read more here.
Keywords: blood lymphocytes; peripheral blood; lymphocytic lymphoma; blood ... See more keywords
Concurrent cutaneous localization of Langerhans cell sarcoma and chronic lymphocytic leukemia/small lymphocytic lymphoma in a patient with a history of chronic lymphocytic leukemia/small lymphocytic lymphoma
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DOI: 10.1111/cup.13571
Abstract: The phenomenon of histiocytic/dendritic cell sarcomas arising through transformation of a pre‐existed lymphoproliferative disease is called transdifferentiation. Langerhans cell sarcoma transdifferentiating from chronic lymphocytic leukemia/small lymphocytic lymphoma is extremely rare and all the reported cases… read more here.
Keywords: lymphocytic leukemia; small lymphocytic; chronic lymphocytic; leukemia small ... See more keywords
Small lymphocytic lymphoma mimicking primary cutaneous marginal zone lymphoma with colonization of germinal center follicles
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DOI: 10.1111/cup.13765
Abstract: Chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) is primarily a disease of older adults and is occasionally an incidental finding on skin biopsies accompanying epithelial neoplasms and insect bite reactions. In rare instances, however, it produces… read more here.
Keywords: lymphoma; marginal zone; cutaneous marginal; primary cutaneous ... See more keywords
Scar induration and ulceration in small lymphocytic lymphoma
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DOI: 10.1111/ijd.15950
Abstract: cutaneous metastatic lesions of 7 months. Skin metastasis typically develops within the first 3 years after primary surgical procedure and is usually asymptomatic. Silent metastasis as a primary sign of rectal cancer is extremely rare.… read more here.
Keywords: rectal cancer; scar induration; cancer; small lymphocytic ... See more keywords
Rosacea‐like cutaneous localization of small lymphocytic lymphoma unmasked by high‐frequency‐ultrasound
Sign Up to like & getrecommendations! Published in 2018 at "Skin Research and Technology"
DOI: 10.1111/srt.12586
Abstract: To the Editor, A 66yearold woman presented with two erythematous plaques on the malar region bilaterally for 2 years. Her medical history was unremarkable and she was taking no medication. Skin lesions had been previously… read more here.
Keywords: localization small; small lymphocytic; cutaneous localization; lymphocytic lymphoma ... See more keywords
Small lymphocytic lymphoma with Reed Sternberg cells: a diagnostic dilemma
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DOI: 10.1136/bcr-2016-218094
Abstract: Reed Sternberg (RS) cells in the setting of small lymphocytic lymphoma (SLL) can complicate the histopathological diagnosis. We report a case of a man aged 54 years who presented with cervical lymphadenopathy. Resection of the… read more here.
Keywords: sternberg cells; lymphoma; small lymphocytic; reed sternberg ... See more keywords
Quercetin Therapy for Selected Patients with PIM1 Kinase-Positive Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma: A Pilot Study
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DOI: 10.1159/000486361
Abstract: We reported that PIM1 kinase is expressed in the lymphocytes of patients with chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL). Quercetin, a naturally occurring flavonoid, is a dietary supplement and inhibits many kinases, including PIM1,… read more here.
Keywords: lymphocytic leukemia; pim1 kinase; study; small lymphocytic ... See more keywords
Concomitant Orbital Tumours: Small Lymphocytic Lymphoma Involving the Lacrimal Gland of a Patient with Clinical Diagnoses of Muir-Torre Syndrome and Extensive Sebaceous Gland Carcinoma of the Ipsilateral Eyelid
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DOI: 10.1159/000500161
Abstract: Background/Aims: We present a case of 2 concomitant tumours, i.e., a sebaceous carcinoma (SC) and a small lymphocytic lymphoma (SLL), in the lacrimal gland of a patient with Muir-Torre syndrome. Methods: Clinical history, orbital examination,… read more here.
Keywords: lymphoma; muir torre; torre syndrome; lacrimal gland ... See more keywords