Small but Mighty: Platelets in NASH and Other Chronic Liver Diseases
Sign Up to like & getrecommendations! Published in 2020 at "Hepatology"
DOI: 10.1002/hep.31101
Abstract: Recent studies have identified several pleiotropic effects of platelets on liver homeostasis and disease distinct from their long-recognized roles in hemostasis and coagulation. Concerns for bleeding have traditionally limited the use of anti-platelet agents in… read more here.
Keywords: disease; small mighty; mighty platelets; chronic liver ... See more keywords
Small but mighty: how minor components drive major biogeochemical cycles.
Sign Up to like & getrecommendations! Published in 2017 at "Environmental microbiology reports"
DOI: 10.1111/1758-2229.12481
Abstract: Coming from a background in iron (Fe) biogeochemistry, I assumed, perhaps naively, that in taking one step over on the periodic table to manganese (Mn) I would find an equal appreciation for this metal within… read more here.
Keywords: minor components; small mighty; mighty minor; components drive ... See more keywords
Small but mighty: Platelets as central effectors of host defense.
Sign Up to like & getrecommendations! Published in 2017 at "Thrombosis and haemostasis"
DOI: 10.1160/th16-12-0921
Abstract: Platelets actively participate in inflammatory processes and drive diseases such as atherosclerosis, rheumatoid arthritis and cancer metastasis. However, platelets also have anti-inflammatory and anti-infective properties, which have received less consideration in the past. In this… read more here.
Keywords: platelets central; defense; central effectors; small mighty ... See more keywords
Small but mighty: T-replete cords for myeloid disease
Sign Up to like & getrecommendations! Published in 2023 at "Blood Advances"
DOI: 10.1182/bloodadvances.2023009746
Abstract: In this issue of Blood Advances, through a multicenter analysis of 367 pediatric patients, Horgan et al have reported that T-replete umbilical cord stem cell (TRCB) transplants against myeloid disease provide superior disease-free survival and… read more here.
Keywords: cord; disease; small mighty; myeloid disease ... See more keywords
REV7: a small but mighty regulator of genome maintenance and cancer development
Sign Up to like & getrecommendations! Published in 2025 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2024.1516165
Abstract: REV7, also known as MAD2B, MAD2L2, and FANCV, is a HORMA-domain family protein crucial to multiple genome stability pathways. REV7’s canonical role is as a member of polymerase ζ, a specialized translesion synthesis polymerase essential… read more here.
Keywords: rev7 small; cancer; genome maintenance; small mighty ... See more keywords
Small but Mighty—Exosomes, Novel Intercellular Messengers in Neurodegeneration
Sign Up to like & getrecommendations! Published in 2022 at "Biology"
DOI: 10.3390/biology11030413
Abstract: Simple Summary Exosomes are biological nanoparticles recently recognized as intercellular messengers. They contain a cargo of lipids, proteins, and RNA. They can transfer their content to not only cells in the vicinity but also to… read more here.
Keywords: intercellular messengers; disease; brain; physiology ... See more keywords
Small but Mighty: Nanobodies in the Fight Against Infectious Diseases
Sign Up to like & getrecommendations! Published in 2025 at "Biomolecules"
DOI: 10.3390/biom15050610
Abstract: Infectious diseases, caused by pathogenic microorganisms and capable of spreading, pose a significant threat to global public health. Developing efficient and cost-effective techniques for treating infectious diseases is crucial in curbing their progression and reducing… read more here.
Keywords: mighty nanobodies; infectious diseases; small mighty; fight infectious ... See more keywords