Solution‐Processed High‐Performance Tetrathienothiophene‐Based Small Molecular Blends for Ambipolar Charge Transport
Sign Up to like & getrecommendations! Published in 2018 at "Advanced Functional Materials"
DOI: 10.1002/adfm.201801025
Abstract: Four soluble dialkylated tetrathienoacene (TTAR)-based small molecular semiconductors featuring the combination of a TTAR central core, π-conjugated spacers comprising bithiophene (bT) or thiophene (T), and with/without cyanoacrylate (CA) end-capping moieties are synthesized and characterized. The… read more here.
Keywords: ttar; charge; small molecular; performance ... See more keywords
Efficient Nonfullerene Polymer Solar Cells Enabled by a Novel Wide Bandgap Small Molecular Acceptor.
Sign Up to like & getrecommendations! Published in 2017 at "Advanced materials"
DOI: 10.1002/adma.201606054
Abstract: A wide bandgap small molecular acceptor, SFBRCN, containing a 3D spirobifluorene core flaked with a 2,1,3-benzothiadiazole (BT) and end-capped with highly electron-deficient (3-ethylhexyl-4-oxothiazolidine-2-yl)dimalononitrile (RCN) units, has been successfully synthesized as a small molecular acceptor (SMA)… read more here.
Keywords: bandgap; wide bandgap; polymer; small molecular ... See more keywords
Hollow Nanomaterials in Advanced Drug Delivery Systems: From Single‐ to Multiple Shells
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Materials"
DOI: 10.1002/adma.202203890
Abstract: Hollow‐structured nanomaterials (HSNMs) have attracted increased interest in biomedical fields, owing to their excellent potential as drug delivery systems (DDSs) for clinical applications. Among HSNMs, hollow multi‐shelled structures (HoMSs) exhibit properties such as high loading… read more here.
Keywords: delivery systems; small molecular; homs based; drug delivery ... See more keywords
Small Molecular Inhibitors Reverse Cancer Metastasis by Blockading Oncogenic PITPNM3
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Science"
DOI: 10.1002/advs.202204649
Abstract: Most cancer‐related deaths are a result of metastasis. The development of small molecular inhibitors reversing cancer metastasis represents a promising therapeutic opportunity for cancer patients. This pan‐cancer analysis identifies oncogenic roles of membrane‐associated phosphatidylinositol transfer… read more here.
Keywords: metastasis; cancer metastasis; pitpnm3; small molecular ... See more keywords
The Solvent Effect on Weak Interactions in Supramolecular Polymers: Differences between Small Molecular Probes and Supramolecular Polymers.
Sign Up to like & getrecommendations! Published in 2020 at "ChemPlusChem"
DOI: 10.1002/cplu.202000400
Abstract: In this minireview, weak interactions that occur in supramolecular polymers are discussed. Combination of weak and strong interactions plays an important role in the construction of supramolecular polymers. It is beneficial to separate the contributions… read more here.
Keywords: weak interactions; effect weak; supramolecular polymers; solvent effect ... See more keywords
Small molecular modulators of JMJD1C preferentially inhibit growth of leukemia cells
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Cancer"
DOI: 10.1002/ijc.32552
Abstract: Histone demethylases are promising therapeutic targets as they play fundamental roles for survival of Mixed lineage leukemia rearranged acute leukemia (MLLr AL). Here we focused on the catalytic Jumonji domain of histone H3 lysine 9… read more here.
Keywords: jdi; leukemia cells; jdi jdi; molecular modulators ... See more keywords
A cross‐sectional study of the FDA approved indications and supporting pivotal trials of small‐molecular kinase inhibitors in cancer therapies with the biomarker of cancer driver gene
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Cancer"
DOI: 10.1002/ijc.34222
Abstract: Cancer precision medicine with biomarker of cancer driver gene (CDG) has been achieved by many small‐molecular kinase inhibitors (SMKIs) approved by the US Food and Drug Administration (FDA). Publicly available FDA documents were collected for… read more here.
Keywords: driver gene; biomarker; small molecular; biomarker cancer ... See more keywords
Bio-Responsive Macromolecular Drug and Small-Molecular Drug Conjugates: Nanoparticulate Prodrugs for Tumor Microenvironment Heterogeneity Management and Therapeutic Response Enhancement.
Sign Up to like & getrecommendations! Published in 2023 at "Small"
DOI: 10.1002/smll.202301656
Abstract: How to break through the poor response of current drug therapy, which often resulted from tumor microenvironment heterogeneity (TMH), remains an enormous challenge in the treatment of critical diseases. In this work, a practical solution… read more here.
Keywords: nanoparticulate prodrugs; drug conjugates; tumor microenvironment; small molecular ... See more keywords
Self-assembled small molecular weight hydrogels of prodrugs
Sign Up to like & getrecommendations! Published in 2017 at "Chinese Chemical Letters"
DOI: 10.1016/j.cclet.2017.04.033
Abstract: Abstract Molecular self-assembly is very ordinary phenomenon in the biological process such as protein folding, DNA encoding and etc. Inspired by this inherent biological process, nanostructure such as nanofibers, nanosphere, and so on formed by… read more here.
Keywords: hydrogels prodrugs; assembled small; self assembled; small molecular ... See more keywords
Recent development of perylene diimide-based small molecular non-fullerene acceptors in organic solar cells
Sign Up to like & getrecommendations! Published in 2017 at "Chinese Chemical Letters"
DOI: 10.1016/j.cclet.2017.08.025
Abstract: Abstract Recently, perylene diimide (PDI) derivatives were attractive as the electron-deficient acceptor materials in non-fullerene organic solar cells since Tang first used a single PDI compound as the n-type semiconductor to fabricate photovoltaic devices in… read more here.
Keywords: organic solar; perylene diimide; non fullerene; small molecular ... See more keywords
Near-infrared small molecular fluorescent dyes for photothermal therapy
Sign Up to like & getrecommendations! Published in 2019 at "Chinese Chemical Letters"
DOI: 10.1016/j.cclet.2019.02.003
Abstract: Abstract Near-infrared (NIR) fluorescent dyes based on small organic molecules are characterized with low cytotoxicity, good biocompatibility and minimum interference from auto-fluorescence background, which are widely used in tumor diagnosis. Intensive research on molecular properties… read more here.
Keywords: photothermal therapy; near infrared; fluorescent dyes; small molecular ... See more keywords