Influence of quaternary cation compound on the size of the Escherichia coli small multidrug resistance protein, EmrE
Sign Up to like & getrecommendations! Published in 2018 at "Biochemistry and Biophysics Reports"
DOI: 10.1016/j.bbrep.2018.02.001
Abstract: EmrE is a member of the small multidrug resistance (SMR) protein family in Escherichia coli. It confers resistance to a wide variety of quaternary cation compounds (QCCs) as an efflux transporter driven by the transmembrane… read more here.
Keywords: quaternary cation; escherichia coli; size; multidrug resistance ... See more keywords
The structural basis of promiscuity in small multidrug resistance transporters
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DOI: 10.1038/s41467-020-19820-8
Abstract: By providing broad resistance to environmental biocides, transporters from the small multidrug resistance (SMR) family drive the spread of multidrug resistance cassettes among bacterial populations. A fundamental understanding of substrate selectivity by SMR transporters is… read more here.
Keywords: basis promiscuity; small multidrug; resistance; multidrug resistance ... See more keywords
Small multidrug resistance protein EmrE phenotypically associates with OmpW, DcrB and YggM for osmotic stress protection by betaine in Escherichia coli.
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DOI: 10.1099/mic.0.001287
Abstract: The small multidrug resistance (SMR) protein EmrE resides in the inner membrane and provides resistance against a wide range of antiseptic quaternary cationic compounds (QCCs) for the Gram-negative bacterium Escherichia coli. We have reported previously… read more here.
Keywords: multidrug resistance; dcrb yggm; small multidrug; protein emre ... See more keywords
Crystal structures of bacterial small multidrug resistance transporter EmrE in complex with structurally diverse substrates
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DOI: 10.1101/2022.01.11.475788
Abstract: Proteins from the bacterial small multidrug resistance (SMR) family are proton-coupled exporters of diverse antiseptics and antimicrobials, including polyaromatic cations and quaternary ammonium compounds. The transport mechanism of the Escherichia coli transporter, EmrE, has been… read more here.
Keywords: bacterial small; multidrug resistance; small multidrug; complex structurally ... See more keywords