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2
Published in 2022 at "FEBS Letters"
DOI: 10.1002/1873-3468.14443
Abstract: The small G protein Arl5b is localised on the trans‐Golgi network (TGN) and regulates endosomes‐to‐TGN transport. Here, we combined in vivo and in vitro techniques to map the interactive partners and near neighbours of Arl5b at the…
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Keywords:
small protein;
proximity labelling;
arl5b;
gfp trap ... See more keywords
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1
Published in 2020 at "Biotechnology Journal"
DOI: 10.1002/biot.202000078
Abstract: Target‐binding small proteins are promising alternatives to conventional monoclonal antibodies (mAbs), offering advantages in terms of tissue penetration and manufacturing costs. Recently, a design strategy to create small proteins called fluctuation‐regulated affinity proteins (FLAPs) consisting…
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Keywords:
protein scaffold;
dual cdr;
cdr derived;
cdr ... See more keywords
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1
Published in 2022 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.1c00798
Abstract: The ability to deliver small protein scaffolds intracellularly could enable the targeting and inhibition of many therapeutic targets that are not currently amenable to inhibition with small-molecule drugs. Here, we report the engineering of small…
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Keywords:
small protein;
cytosolic delivery;
inhibition;
protein scaffolds ... See more keywords
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0
Published in 2021 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2012277118
Abstract: Significance During genome analysis, genes encoding small proteins are frequently neglected. Accordingly, small proteins have remained underinvestigated in all domains of life. Based on a previous systematic search for such genes, we present the functional…
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Keywords:
nitrogen;
degradation;
nbld;
factor ... See more keywords
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1
Published in 2022 at "Autophagy"
DOI: 10.1080/15548627.2022.2132707
Abstract: RHOA (ras homolog family member A) is a small G-protein that regulates a range of cellular processes including cell growth and survival. RHOA is a proximal downstream effector of G protein-coupled receptor coupling to GNA12/Gα12-GNA13/Gα13…
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Keywords:
small protein;
protein stability;
rhoa;
protein ... See more keywords
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2
Published in 2022 at "European Journal of Neuroscience"
DOI: 10.1111/ejn.15855
Abstract: Although forgetting was once regarded as a passive decline in memory and an occasional source of embarrassment, recent research suggests that it is an active biological process of removing outdated or irrelevant memories via activation…
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Keywords:
small protein;
caenorhabditis elegans;
rac;
jnk ... See more keywords
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1
Published in 2017 at "Journal of Bacteriology"
DOI: 10.1128/jb.00869-16
Abstract: ABSTRACT The bacterial small RNA (sRNA) SgrS has been a fruitful model for discovery of novel RNA-based regulatory mechanisms and new facets of bacterial physiology and metabolism. SgrS is one of only a few characterized…
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Keywords:
sgrt;
activity;
protein sgrt;
transport activity ... See more keywords
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1
Published in 2022 at "PLoS Genetics"
DOI: 10.1371/journal.pgen.1010074
Abstract: Gene organization in operons enables concerted transcription of functionally related genes and efficient control of cellular processes. Typically, an operon is transcribed as a polycistronic mRNA that is translated into corresponding proteins. Here, we identify…
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Keywords:
virulence;
small protein;
gene;
virulence program ... See more keywords
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1
Published in 2018 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2018.01994
Abstract: A monocistronic small protein, BpOF4_01690, was annotated in alkaliphilic Bacillus pseudofirmus OF4. It comprises 59 amino acids and is hydrophobic. Importantly, homologs of this protein were identified only in alkaliphiles. In this study, a mutant…
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Keywords:
bacillus pseudofirmus;
alkaliphilic bacillus;
bpof4 01690;
protein bpof4 ... See more keywords
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1
Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.900234
Abstract: The small protein B (SmpB), previously acting as a ribosome rescue factor for translation quality control, is required for cell viability in bacteria. Here, our study reveals that SmpB possesses new function which regulates the…
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Keywords:
peptide aptamer;
outer membrane;
small protein;
aptamer pa3 ... See more keywords
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2
Published in 2023 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2022.1065627
Abstract: Rabproteins are the largest members of the small G protein family and are widely distributed in eukaryotes. It comprises eight subfamilies and is responsible for regulating vesicle transport, plant growth and development, and biotic and…
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Keywords:
small protein;
potato;
expression;
resistance ... See more keywords