Identifying New Small Proteins in Escherichia coli
Sign Up to like & getrecommendations! Published in 2018 at "Proteomics"
DOI: 10.1002/pmic.201700064
Abstract: The number of small proteins (SPs) encoded in the Escherichia coli genome is unknown, as current bioinformatics and biochemical techniques make short gene and small protein identification challenging. One method of small protein identification involves… read more here.
Keywords: escherichia coli; small proteins; protein synthesis; identifying new ... See more keywords
Enrichment and identification of small proteins in a simplified human gut microbiome.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of proteomics"
DOI: 10.1016/j.jprot.2019.103604
Abstract: Small proteins (sProteins) with a size of 100 amino acids and less are involved in major biological processes and play an important role in different bacteria. Despite the increasing interest in them, the data on… read more here.
Keywords: human gut; small proteins; gut microbiome; microbiome ... See more keywords
Lipid Nanoparticle Delivery of Small Proteins for Potent In Vivo RAS Inhibition.
Sign Up to like & getrecommendations! Published in 2023 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.3c01501
Abstract: Mutated RAS proteins are potent oncogenic drivers and have long been considered "undruggable". While RAS-targeting therapies have recently shown promise, there remains a clinical need for RAS inhibitors with more diverse targets. Small proteins represent… read more here.
Keywords: nanoparticle delivery; small proteins; lipid nanoparticle; delivery small ... See more keywords
Stop CRYing! Inhibition of cryptochrome function by small proteins.
Sign Up to like & getrecommendations! Published in 2022 at "Biochemical Society transactions"
DOI: 10.1042/bst20190062
Abstract: Plants can detect the presence of light using specialised photoreceptor proteins. These photoreceptors measure the intensity of light, but they can also respond to different spectra of light and thus 'see' different colours. Cryptochromes, which… read more here.
Keywords: light; small proteins; inhibition cryptochrome; inhibition ... See more keywords
SmProt: a database of small proteins encoded by annotated coding and non‐coding RNA loci
Sign Up to like & getrecommendations! Published in 2018 at "Briefings in Bioinformatics"
DOI: 10.1093/bib/bbx005
Abstract: &NA; Small proteins is the general term for proteins with length shorter than 100 amino acids. Identification and functional studies of small proteins have advanced rapidly in recent years, and several studies have shown that… read more here.
Keywords: proteins encoded; small proteins; database small; smprot database ... See more keywords
Small Proteins; Big Questions
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Bacteriology"
DOI: 10.1128/jb.00341-21
Abstract: In recent years, there has been increased appreciation that a whole category of proteins, small proteins of around 50 amino acids or fewer in length, has been missed by annotation as well as by genetic… read more here.
Keywords: proteins big; big questions; bacteriology; questions small ... See more keywords
Numaswitch – an efficient high-titer expression platform to produce peptides and small proteins
Sign Up to like & getrecommendations! Published in 2021 at "AMB Express"
DOI: 10.21203/rs.3.rs-237571/v1
Abstract: The production of peptides as active pharmaceutical ingredients (APIs) by recombinant technologies is of emerging interest. A reliable production platform, however, is still missing due the inherent characteristics of peptides such as proteolytic sensitivity, aggregation… read more here.
Keywords: numaswitch efficient; production; platform; small proteins ... See more keywords
Vascular Endothelial Growth Factor-A Exerts Diverse Cellular Effects via Small G Proteins, Rho and Rap
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms19041203
Abstract: Vascular endothelial growth factors (VEGFs) include five molecules (VEGF-A, -B, -C, -D, and placental growth factor), and have various roles that crucially regulate cellular functions in many kinds of cells and tissues. Intracellular signal transduction… read more here.
Keywords: vascular endothelial; endothelial growth; small proteins; diverse cellular ... See more keywords
Rescue of Escherichia coli auxotrophy by de novo small proteins
Sign Up to like & getrecommendations! Published in 2022 at "eLife"
DOI: 10.7554/elife.78299
Abstract: Increasing numbers of small proteins with diverse physiological roles are being identified and characterized in both prokaryotic and eukaryotic systems, but the origins and evolution of these proteins remain unclear. Recent genomic sequence analyses in… read more here.
Keywords: coli auxotrophy; rescue escherichia; small proteins; escherichia coli ... See more keywords