Interactions between short and long noncoding RNAs
Sign Up to like & getrecommendations! Published in 2018 at "FEBS Letters"
DOI: 10.1002/1873-3468.13085
Abstract: It is now evident that noncoding RNAs play key roles in regulatory networks determining cell fate and behavior, in a myriad of different conditions, and across all species. Among these noncoding RNAs are short RNAs,… read more here.
Keywords: small rna; long noncoding; short long; interactions short ... See more keywords
Small RNA sequencing in hypoxic naked mole‐rat hearts suggests microRNA regulation of RNA‐ and translation‐related processes
Sign Up to like & getrecommendations! Published in 2022 at "FEBS Letters"
DOI: 10.1002/1873-3468.14499
Abstract: The naked mole‐rat (Heterocephalus glaber) regularly endures intermittent periods of hypoxia in its burrows, surviving in part due to metabolic rate depression (MRD)—a strategy of conserving cellular resources by downregulating nonessential gene expression and reorganizing cellular… read more here.
Keywords: rna sequencing; naked mole; translation related; small rna ... See more keywords
Inheritance and maintenance of small RNA‐mediated epigenetic effects
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DOI: 10.1002/bies.202100284
Abstract: Heritable traits are predominantly encoded within genomic DNA, but it is now appreciated that epigenetic information is also inherited through DNA methylation, histone modifications, and small RNAs. Several examples of transgenerational epigenetic inheritance of traits… read more here.
Keywords: information; maintenance small; epigenetic information; inheritance maintenance ... See more keywords
Screening for differentially expressed microRNAs in BALF and blood samples of infected COVID‐19 ARDS patients by small RNA deep sequencing
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24672
Abstract: The pandemic COVID‐19 has caused a high mortality rate and poses a significant threat to the population of the entire world. Due to the novelty of this disease, the pathogenic mechanism of the disease and… read more here.
Keywords: screening differentially; rna deep; differentially expressed; ards patients ... See more keywords
Extracellular Vesicle Capture by AnTibody of CHoice and Enzymatic Release (EV‐CATCHER): A customizable purification assay designed for small‐RNA biomarker identification and evaluation of circulating small‐EVs
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Extracellular Vesicles"
DOI: 10.1002/jev2.12110
Abstract: Abstract Circulating nucleic acids, encapsulated within small extracellular vesicles (EVs), provide a remote cellular snapshot of biomarkers derived from diseased tissues, however selective isolation is critical. Current laboratory‐based purification techniques rely on the physical properties… read more here.
Keywords: small rna; evs; purification assay; small evs ... See more keywords
Androgens alter the heterogeneity of small extracellular vesicles and the small RNA cargo in prostate cancer
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Extracellular Vesicles"
DOI: 10.1002/jev2.12136
Abstract: Abstract Proliferation and survival of prostate cancer cells are driven by the androgen receptor (AR) upon binding to androgen steroid hormones. Manipulating the AR signalling axis is the focus for prostate cancer therapy; thus, it… read more here.
Keywords: extracellular vesicles; small rna; prostate cancer; cancer ... See more keywords
Systematic identification and characterization of viral small RNAs from small RNA‐Seq data
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Medical Virology"
DOI: 10.1002/jmv.28617
Abstract: Virus‐encoded small RNAs (vsRNAs) have been reported to play an important role in viral infections. Unfortunately, there is still a lack of a systematic characterization and resource of vsRNAs. Herein, we identified a total of… read more here.
Keywords: seq data; vsrnas identified; rna seq; small rna ... See more keywords
Transposon mutagenesis in Mycobacterium kansasii links a small RNA gene to colony morphology and biofilm formation and identifies 9,885 intragenic insertions that do not compromise colony outgrowth
Sign Up to like & getrecommendations! Published in 2020 at "MicrobiologyOpen"
DOI: 10.1002/mbo3.988
Abstract: Mycobacterium kansasii (Mk) is a resilient opportunistic human pathogen that causes tuberculosis‐like chronic pulmonary disease and mortality stemming from comorbidities and treatment failure. The standard treatment of Mk infections requires costly, long‐term, multidrug courses with… read more here.
Keywords: small rna; colony; transposon mutagenesis; mycobacterium kansasii ... See more keywords
Small RNA In Situ Hybridizations on Sections of Arabidopsis Embryos.
Sign Up to like & getrecommendations! Published in 2020 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-0342-0_7
Abstract: Small RNAs mediate posttranscriptional gene silencing in plants and animals. This often occurs in specific cell or tissue types and can be necessary for their differentiation. Determining small RNA (sRNA) localization patterns at cellular resolution… read more here.
Keywords: small rna; hybridizations sections; sections arabidopsis; rna situ ... See more keywords
Integrated Genome-Scale Analysis and Northern Blot Detection of Retrotransposon siRNAs Across Plant Species.
Sign Up to like & getrecommendations! Published in 2020 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-0712-1_23
Abstract: Cells have sophisticated RNA-directed mechanisms to regulate genes, destroy viruses, or silence transposable elements (TEs). In terrestrial plants, a specialized non-coding RNA machinery involving RNA polymerase IV (Pol IV) and small interfering RNAs (siRNAs) targets… read more here.
Keywords: small rna; analysis; rna; sirnas ... See more keywords
Rapid and Specific Purification of Argonaute-Small RNA Complexes from Rice for Slicer Activity.
Sign Up to like & getrecommendations! Published in 2022 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1835-6_14
Abstract: Argonaute (AGO) proteins associate with small RNAs (sRNAs) to form an RNA-induced silencing complex (RISC). The ribonuclease (slicer) activity of AGOs is required for the sRNA-complementary target cleavage, which is important for RISC-mediated RNA silencing, especially… read more here.
Keywords: slicer; purification; slicer activity; activity ... See more keywords