Genomic and transcriptomic characterization of desmoplastic small round cell tumors
Sign Up to like & getrecommendations! Published in 2021 at "Genes"
DOI: 10.1002/gcc.22955
Abstract: Desmoplastic small round cell tumor (DSRCT) is a highly aggressive soft tissue tumor primarily affecting children and young adults. Most cases display a pathognomonic EWSR1‐WT1 gene fusion, presumably constituting the primary driver event. Little is,… read more here.
Keywords: desmoplastic small; round cell; tumor; small round ... See more keywords
A national analysis of patterns of care and outcomes for adults diagnosed with desmoplastic small round cell tumors in the United States
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Surgical Oncology"
DOI: 10.1002/jso.25426
Abstract: Because of the rarity of desmoplastic small round cell tumors (DSRCT), there is a lack of data describing patterns of care and survival for these patients. Using a national tumor registry, the current study sought… read more here.
Keywords: round cell; small round; patterns care; desmoplastic small ... See more keywords
Machine learning to differentiate small round cell malignant tumors and non-small round cell malignant tumors of the nasal and paranasal sinuses using apparent diffusion coefficient values
Sign Up to like & getrecommendations! Published in 2022 at "European Radiology"
DOI: 10.1007/s00330-021-08465-w
Abstract: We used radiomics feature–based machine learning classifiers of apparent diffusion coefficient (ADC) maps to differentiate small round cell malignant tumors (SRCMTs) and non-SRCMTs of the nasal and paranasal sinuses. A total of 267 features were… read more here.
Keywords: small round; cell malignant; feature; malignant tumors ... See more keywords
Usefulness of NKX2.2 Immunohistochemistry for Distinguishing Ewing Sarcoma from Other Sinonasal Small Round Blue Cell Tumors
Sign Up to like & getrecommendations! Published in 2017 at "Head and Neck Pathology"
DOI: 10.1007/s12105-017-0830-1
Abstract: AbstractNKX2.2 is a new immunohistochemical marker that has been reported to be sensitive and specific for Ewing sarcoma (ES). It has not, however, been investigated specifically in the sinonasal small round blue cell tumor (SRBCT)… read more here.
Keywords: small round; ewing sarcoma; carcinomas; cell ... See more keywords
Intra-abdominal desmoplastic small round cell tumour in a 56-year-old female: Case report of a very rare presentation of an unusual tumour
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Surgery Case Reports"
DOI: 10.1016/j.ijscr.2021.01.058
Abstract: Highlights • Intra-abdominal desmoplastic small round cell tumour is a rare tumour not previously reported in a female over the age of 50.• Disparity between radiological and histological appearances should prompt further review and investigation.•… read more here.
Keywords: cell tumour; round cell; small round; abdominal desmoplastic ... See more keywords
Can we cure patients with abdominal Desmoplastic Small Round Cell Tumor? Results of a retrospective multicentric study on 100 patients.
Sign Up to like & getrecommendations! Published in 2019 at "Surgical oncology"
DOI: 10.1016/j.suronc.2019.04.002
Abstract: BACKGROUND Despite being associated with a very poor prognosis, long-term survivors across all series of Desmoplastic Small Round Cell Tumor (DSRCT) have been reported. AIM OF THE STUDY To analyze patients 'characteristics associated with a… read more here.
Keywords: desmoplastic small; small round; cell tumor; round cell ... See more keywords
Small round blue cell tumors of the sinonasal tract: a differential diagnosis approach
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DOI: 10.1038/modpathol.2016.119
Abstract: One of the most challenging diagnostic categories within tumors of the sinonasal tract is the small round blue cell tumors. Biopsies are usually small and limited, resulting in considerable diagnostic difficulty for practicing surgical pathologists.… read more here.
Keywords: round blue; blue cell; diagnosis; small round ... See more keywords
Transcriptome analysis of desmoplastic small round cell tumors identifies actionable therapeutic targets: a report from the Children’s Oncology Group
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-69015-w
Abstract: To further understand the molecular pathogenesis of desmoplastic small round cell tumor (DSRCT), a fatal malignancy occurring primarily in adolescent/young adult males, we used next-generation RNA sequencing to investigate the gene expression profiles intrinsic to… read more here.
Keywords: therapeutic targets; round cell; small round; desmoplastic small ... See more keywords
Trabectedin-irinotecan, a potentially promising combination in relapsed desmoplastic small round cell tumor: report of two cases
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Chemotherapy"
DOI: 10.1080/1120009x.2022.2067706
Abstract: Abstract Effective new drugs are urgently needed for desmoplastic small round cell tumor (DSRCT), an extremely rare and aggressive disease with a generally poor prognosis. We describe two heavily-pretreated young patients with advanced-stage DSRCT given… read more here.
Keywords: cell tumor; desmoplastic small; round cell; small round ... See more keywords
Desmoplastic small round cell tumor: from state of the art to future clinical prospects
Sign Up to like & getrecommendations! Published in 2023 at "Expert Review of Anticancer Therapy"
DOI: 10.1080/14737140.2023.2200171
Abstract: ABSTRACT Introduction Desmoplastic small round cell tumor (DSRCT) is an extremely rare and highly aggressive soft tissue sarcoma, presenting mainly in male adolescents and young adults with multiple nodules disseminated within the abdominopelvic cavity. Despite… read more here.
Keywords: cell tumor; desmoplastic small; round cell; small round ... See more keywords
Mediastinal desmoplastic small round cell tumor
Sign Up to like & getrecommendations! Published in 2020 at "Medicine"
DOI: 10.1097/md.0000000000022921
Abstract: Abstract Rationale: Desmoplastic small round cell tumor (DSRCT) is a rare distinct tumor with a high-grade malignancy. Patient concerns: A 51-year-old male visited a local hospital in April 2016 complaining of shortness of breath, chest… read more here.
Keywords: cell tumor; small round; tumor; round cell ... See more keywords