Improving Aggregation Control of Recombinant Adeno‐Associated Virus Serotype 2 (rAAV2) With Small Sugars and Ionic Salts
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DOI: 10.1002/biot.70157
Abstract: Two persistent challenges in adeno‐associated virus (AAV) manufacturing are AAV particle aggregation and the separation of full and empty AAV capsids in ion‐exchange (IEX) chromatography processes, which add to AAV purification, formulation, and quality control… read more here.
Keywords: adeno associated; control; small sugars; associated virus ... See more keywords