Antibodies to small ubiquitin-like modifier activating enzyme are associated with a diagnosis of dermatomyositis: results from an unselected cohort
Sign Up to like & getrecommendations! Published in 2018 at "Immunologic Research"
DOI: 10.1007/s12026-018-9006-7
Abstract: The aim of this study was to examine the frequency and significance of antibodies targeting the small ubiquitin-like modifier 1 activating enzyme (SAE) in patients under serologic evaluation for idiopathic inflammatory myopathies. Patient sera (nā=ā17)… read more here.
Keywords: ubiquitin like; small ubiquitin; like modifier; activating enzyme ... See more keywords
Atomic Force Microscopy and Spectroscopic Ellipsometry combined analysis of Small Ubiquitin-like Modifier adsorption on functional monolayers
Sign Up to like & getrecommendations! Published in 2017 at "Applied Surface Science"
DOI: 10.1016/j.apsusc.2016.10.195
Abstract: Abstract The comprehension of mechanisms of interaction between functional layers and proteins is relevant for the development of sensitive and precise biosensors. Here we report our study which combines Atomic Force Microscopy and Spectroscopic Ellipsometry… read more here.
Keywords: spectroscopic ellipsometry; microscopy; small ubiquitin; force microscopy ... See more keywords
Small-molecule inhibitors targeting small ubiquitin-like modifier pathway for the treatment of cancers and other diseases.
Sign Up to like & getrecommendations! Published in 2022 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2022.114227
Abstract: SUMOylation is a key post-translational modification that involves the covalent attachment of small ubiquitin-like modifier (SUMO) to the lysine residues of target proteins. The well-balanced SUMOylation is essential for normal cellular behaviors, while disturbance of… read more here.
Keywords: cancers diseases; small ubiquitin; like modifier; ubiquitin like ... See more keywords
GW28-e0140 Knockout of Small Ubiquitin-Like Modifier 1 Protects the Mice from Pressure Overload-Induced Cardiac Hypertrophy and Dysfunction
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the American College of Cardiology"
DOI: 10.1016/j.jacc.2017.07.014
Abstract: Small ubiquitin-like modifier (SUMO1-3) conjugation (SUMOylation), a post-translational modification, modulates activity of a large number of nuclear proteins, including transcriptional factors and chromatin-associated proteins, and plays a crucial role in heart development and pathogenesis of… read more here.
Keywords: e0140 knockout; ubiquitin like; small ubiquitin; like modifier ... See more keywords
Progress of small ubiquitin-related modifiers in kidney diseases
Sign Up to like & getrecommendations! Published in 2019 at "Chinese Medical Journal"
DOI: 10.1097/cm9.0000000000000094
Abstract: Objective: Small ubiquitin-related modifiers (SUMOs) are a group of post-translational modification proteins extensively expressed in eukaryotes. Abnormal SUMOylation can lead to the development of various diseases. This article summarizes the progress on research of the… read more here.
Keywords: related modifiers; kidney diseases; small ubiquitin; sumoylation ... See more keywords
Large-Scale Purification of Small Ubiquitin-Like Modifier (SUMO)-Modified Proteins from Schizosaccharomyces pombe.
Sign Up to like & getrecommendations! Published in 2017 at "Cold Spring Harbor protocols"
DOI: 10.1101/pdb.prot091603
Abstract: Covalent protein modification by sumoylation (i.e., addition of small ubiquitin-like modifiers [SUMOs]) regulates a broad spectrum of critical functions in eukaryotic cells; however, usually ā¤1% of a given protein is modified as a result of… read more here.
Keywords: large scale; purification small; scale purification; ubiquitin like ... See more keywords
Identification and expression analysis of a new small ubiquitin-like modifier from Taenia pisiformis.
Sign Up to like & getrecommendations! Published in 2022 at "Experimental parasitology"
DOI: 10.2139/ssrn.4188477
Abstract: The small ubiquitin-like modifier (SUMO) plays important roles, with the SUMOylation pathway as one of its core components. In the present work, a single SUMO gene was initially identified from Taenia pisiformis and designated as… read more here.
Keywords: tpsumo; ubiquitin like; like modifier; small ubiquitin ... See more keywords