Temporal Dynamics of Cortical Microinfarcts in Cerebral Small Vessel Disease.
Sign Up to like & getrecommendations! Published in 2020 at "JAMA neurology"
DOI: 10.1001/jamaneurol.2019.5106
Abstract: Importance Neuropathology studies show a high prevalence of cortical microinfarcts (CMIs) in aging individuals, especially in patients with cerebrovascular disease and dementia. However, most, are invisible on T1- and T2-weighted magnetic resonance imaging (MRI), raising… read more here.
Keywords: cerebral small; cmi; small vessel; cortical microinfarcts ... See more keywords
Framework for Clinical Trials in Cerebral Small Vessel Disease (FINESSE): A Review.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA neurology"
DOI: 10.1001/jamaneurol.2022.2262
Abstract: Importance Cerebral small vessel disease (SVD) causes a quarter of strokes and is the most common pathology underlying vascular cognitive impairment and dementia. An important step to developing new treatments is better trial methodology. Disease… read more here.
Keywords: vessel disease; clinical trials; methodology; cerebral small ... See more keywords
Predictors of Atrial Fibrillation in Patients With Stroke Attributed to Large- or Small-Vessel Disease
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Neurology"
DOI: 10.1001/jamaneurol.2022.4038
Abstract: This prespecified analysis of the Stroke of Known Cause and Underlying Atrial Fibrillation (STROKE AF) randomized clinical trial investigates the association of commonly assessed risk factors with undiagnosed atrial fibrillation in patients with ischemic stroke… read more here.
Keywords: fibrillation patients; vessel disease; fibrillation; small vessel ... See more keywords
Ischemia in intracerebral hemorrhage: A comparative study of small‐vessel and large‐vessel diseases
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.51497
Abstract: This study aimed to compare effects of cerebral small‐vessel disease (cSVD) burden and cerebral artery stenosis (CAS) on acute ischemia in intracerebral hemorrhage (ICH) and their interaction with mean arterial pressure (MAP) change. read more here.
Keywords: study; ischemia intracerebral; intracerebral hemorrhage; small vessel ... See more keywords
Contribution of acute infarcts to cerebral small vessel disease progression
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Neurology"
DOI: 10.1002/ana.25556
Abstract: To determine the contribution of acute infarcts, evidenced by diffusion‐weighted imaging positive (DWI+) lesions, to progression of white matter hyperintensities (WMH) and other cerebral small vessel disease (SVD) markers. read more here.
Keywords: cerebral small; contribution acute; small vessel; acute infarcts ... See more keywords
Mimics of Pediatric Small Vessel Primary Angiitis of the Central Nervous System
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Neurology"
DOI: 10.1002/ana.26531
Abstract: Small vessel primary angiitis of the central nervous system is a rare and often severe disease characterized by central nervous system‐restricted inflammatory vasculitis on histopathology. Diagnosis requires brain biopsy for confirmation and is suggested prior… read more here.
Keywords: vessel primary; central nervous; small vessel; primary angiitis ... See more keywords
Long‐term outcomes after stent implantation in very small vessel coronary artery disease
Sign Up to like & getrecommendations! Published in 2023 at "Clinical Cardiology"
DOI: 10.1002/clc.24000
Abstract: Percutaneous coronary interventions (PCI) in very small vessel lesions represent an intriguing aspect of coronary artery disease (CAD). Uncertainty still exists in stent implantation in very small caliber vessels. This study aimed to evaluate the… read more here.
Keywords: long term; artery disease; small vessel; implantation small ... See more keywords
Are neuropsychiatric symptoms a marker of small vessel disease progression in older adults? Evidence from the Lothian Birth Cohort 1936
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Geriatric Psychiatry"
DOI: 10.1002/gps.5855
Abstract: Neuropsychiatric symptoms could form part of an early cerebral small vessel disease prodrome that is detectable before stroke or dementia onset. We aimed to identify whether apathy, depression, anxiety, and subjective memory complaints associate with… read more here.
Keywords: neuropsychiatric symptoms; vessel disease; symptoms marker; small vessel ... See more keywords
Cerebral Microbleeds Are Associated With Increased Brain Iron and Cognitive Impairment in Patients With Cerebral Small Vessel Disease: A Quantitative Susceptibility Mapping Study
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Magnetic Resonance Imaging"
DOI: 10.1002/jmri.28092
Abstract: Cerebral microbleeds (CMBs) have been recognized to play an important role in cognitive impairment of cerebral small vessel disease (CSVD) patients. However, the mechanism of this effect is still unclear. read more here.
Keywords: cerebral microbleeds; vessel disease; cerebral small; small vessel ... See more keywords
Report of two pedigrees with heterozygous HTRA1 variants‐related cerebral small vessel disease and literature review
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DOI: 10.1002/mgg3.2032
Abstract: Biallelic HTRA1 pathogenic variants are associated with autosomal recessive cerebral arteriopathy with subcortical infarcts and leukoencephalopathy (CARASIL). Recent studies have indicated that heterozygous HTRA1 variants are related to autosomal dominant hereditary cerebral small vessel disease… read more here.
Keywords: variants related; heterozygous htra1; vessel disease; htra1 variants ... See more keywords
Contrast-agent-free State-of-the-art Magnetic Resonance Imaging on Cerebral Small Vessel Disease - Part 1: ASL, IVIM, and CVR.
Sign Up to like & getrecommendations! Published in 2022 at "NMR in biomedicine"
DOI: 10.1002/nbm.4742
Abstract: Cerebral small vessel disease (cSVD), a common cause of stroke and dementia, is traditionally considered the small vessel equivalent of large artery occlusion or rupture that leads to cortical and subcortical brain damage. Microvessel endothelial… read more here.
Keywords: cvr; resonance imaging; magnetic resonance; small vessel ... See more keywords