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Published in 2020 at "JAMA neurology"
DOI: 10.1001/jamaneurol.2019.5106
Abstract: Importance Neuropathology studies show a high prevalence of cortical microinfarcts (CMIs) in aging individuals, especially in patients with cerebrovascular disease and dementia. However, most, are invisible on T1- and T2-weighted magnetic resonance imaging (MRI), raising… read more here.
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Published in 2022 at "JAMA neurology"
DOI: 10.1001/jamaneurol.2022.2262
Abstract: Importance Cerebral small vessel disease (SVD) causes a quarter of strokes and is the most common pathology underlying vascular cognitive impairment and dementia. An important step to developing new treatments is better trial methodology. Disease… read more here.
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Published in 2022 at "JAMA Neurology"
DOI: 10.1001/jamaneurol.2022.4038
Abstract: This prespecified analysis of the Stroke of Known Cause and Underlying Atrial Fibrillation (STROKE AF) randomized clinical trial investigates the association of commonly assessed risk factors with undiagnosed atrial fibrillation in patients with ischemic stroke… read more here.
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Published in 2022 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.51497
Abstract: This study aimed to compare effects of cerebral small‐vessel disease (cSVD) burden and cerebral artery stenosis (CAS) on acute ischemia in intracerebral hemorrhage (ICH) and their interaction with mean arterial pressure (MAP) change. read more here.
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Published in 2019 at "Annals of Neurology"
DOI: 10.1002/ana.25556
Abstract: To determine the contribution of acute infarcts, evidenced by diffusion‐weighted imaging positive (DWI+) lesions, to progression of white matter hyperintensities (WMH) and other cerebral small vessel disease (SVD) markers. read more here.
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Published in 2022 at "Annals of Neurology"
DOI: 10.1002/ana.26531
Abstract: Small vessel primary angiitis of the central nervous system is a rare and often severe disease characterized by central nervous system‐restricted inflammatory vasculitis on histopathology. Diagnosis requires brain biopsy for confirmation and is suggested prior… read more here.
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Published in 2024 at "Annals of Neurology"
DOI: 10.1002/ana.26940
Abstract: Primary angiitis of the central nervous system (PACNS) is a rare vasculitis restricted to the brain, spinal cord, and leptomeninges. This study aimed to describe the imaging characteristics of patients with small vessel PACNS (SV‐PACNS)… read more here.
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Published in 2025 at "Annals of Neurology"
DOI: 10.1002/ana.27249
Abstract: male patient in his 50s with a history of hypertension and previous smoking presented for evaluation of recurrent subcortical ischemic strokes in the last 8 years, all presenting with right sided pure motor hemiparesis. The… read more here.
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Published in 2025 at "Brain and Behavior"
DOI: 10.1002/brb3.70342
Abstract: It is suggested that cerebral small vessel disease (SVD) plays a role in strokes and dementia. Retinal microvasculature imaged by optical coherence tomography angiography (OCTA) is suggested to be associated with cerebral microvessels. We measured… read more here.
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Published in 2023 at "Clinical Cardiology"
DOI: 10.1002/clc.24000
Abstract: Percutaneous coronary interventions (PCI) in very small vessel lesions represent an intriguing aspect of coronary artery disease (CAD). Uncertainty still exists in stent implantation in very small caliber vessels. This study aimed to evaluate the… read more here.
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Published in 2024 at "Clinical Cardiology"
DOI: 10.1002/clc.70043
Abstract: Patients with small vessels who undergo percutaneous coronary intervention (PCI) with subsequent multiple implantation of drug‐eluting stents remain at a higher risk of unfavorable outcomes. In complex cases where maintaining flow to all side branches… read more here.