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   Articles with "smallanthus sonchifolius" as a keyword



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Yacon fructans (Smallanthus sonchifolius) extraction, characterization and activation of macrophages to phagocyte yeast cells.

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recommendations! Published in 2018 at "International journal of biological macromolecules"

DOI: 10.1016/j.ijbiomac.2017.11.034

Abstract: Yacon (Smallanthus sonchifolius) originates from the Andean region and has spread across South America, Europe and Japan. In contrast with most roots, yacon stores its carbohydrates in fructooligosaccharides (FOS) and contains approximately 37% of FOS… read more here.

Keywords: smallanthus sonchifolius; fos; yacon fructans; sonchifolius extraction ... See more keywords

Yacon (Smallanthus sonchifolius)-based product increases fecal short-chain fatty acids and enhances regulatory T cells by downregulating RORγt in the colon of BALB/c mice

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recommendations! Published in 2019 at "Journal of Functional Foods"

DOI: 10.1016/j.jff.2019.02.039

Abstract: Abstract Although yacon (Smallanthus sonchifolius) is a known source of prebiotics (fructooligosaccharides (FOS) and inulin) and phenolic compounds beneficial to gut microbiota and intestinal immune response modulation, its regulatory mechanisms still remain unclear. Therefore, we… read more here.

Keywords: smallanthus sonchifolius; mice; short chain; based product ... See more keywords

Clastogenic, aneugenic and cytostatic effects of Smallanthus sonchifolius leaf extract in a human tumoral cell line.

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recommendations! Published in 2025 at "Natural product research"

DOI: 10.1080/14786419.2025.2508830

Abstract: Smallanthus sonchifolius leaf extracts show potential health benefits but also exhibit cytotoxicity in vitro. This study evaluated the genotoxic effects of a crude extract rich in sesquiterpene lactones (CLM) in HeLa cells. HPLC/MS-MS analysis identified… read more here.

Keywords: smallanthus sonchifolius; clastogenic aneugenic; cell; aneugenic cytostatic ... See more keywords

New sesquiterpene derivatives from stems and leaves of Smallanthus sonchifolius.

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recommendations! Published in 2025 at "Natural product research"

DOI: 10.1080/14786419.2025.2528154

Abstract: From the MeOH residue of Smallanthus sonchifolius stems and leaves, three new sesquiterpene derivatives, namely smallantholides A - C (1 - 3), and two know phenyl propanoid glycosides (4 and 5), were isolated using various chromatographic techniques. The structural… read more here.

Keywords: new sesquiterpene; sesquiterpene derivatives; derivatives stems; smallanthus sonchifolius ... See more keywords

IN SILICO INVESTIGATION OF SMALLANTHUS SONCHIFOLIUS COMPOUNDS AS DPP-4 INHIBITORS FOR ANTIDIABETIC MECHANISMS

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recommendations! Published in 2025 at "International Journal of Applied Pharmaceutics"

DOI: 10.22159/ijap.2025v17i2.52741

Abstract: Objective: Smallanthus sonchifolius has been scientifically demonstrated to possess antidiabetic activity through the inhibition of DPP-4 in in vitro studies. However, there is still a lack of comprehensive research identifying the specific bioactive compounds responsible… read more here.

Keywords: investigation; molecular dynamics; dpp inhibitors; smallanthus sonchifolius ... See more keywords

Quantification of Enhydrin and Uvedalin in the Ethanolic Extract of Smallanthus sonchifolius Leaves Validated by the HPLC Method

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recommendations! Published in 2023 at "Molecules"

DOI: 10.3390/molecules28041913

Abstract: Yacon leaf (Smallanthus sonchifolius, Asteraceae) ethanolic extracts are widely used in herbal medicine preparation for diabetes. They contain two sesquiterpene lactones (enhydrin (1) and uvedalin (2)) as major bioactive compounds. To provide a suitable method… read more here.

Keywords: extract; smallanthus sonchifolius; enhydrin uvedalin; hplc method ... See more keywords

Antioxidant and inhibitory activities of α-amylase, α-glucosidase, and G6Pase from Smallanthus sonchifolius tuber extract as a potential antidiabetic agent

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recommendations! Published in 2024 at "Journal of Herbmed Pharmacology"

DOI: 10.34172/jhp.2025.52551

Abstract: Introduction: Diabetes mellitus (DM) is a chronic condition with free radicals and carbohydrate-hydrolyzing enzymes playing key roles in its progression. Yacon or Smallanthus sonchifolius (Poepp.) H.Rob, a low-sugar crop, has shown promising bioactivities. This research… read more here.

Keywords: tuber extract; smallanthus sonchifolius; glucosidase g6pase; amylase glucosidase ... See more keywords