Pan-SMARCA/PB1 Bromodomain Inhibitors and Their Role in Regulating Adipogenesis.
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DOI: 10.1021/acs.jmedchem.0c01242
Abstract: Accessibility of the human genome is modulated by the ATP-driven SWI/SNF chromatin remodeling multiprotein complexes BAF (BRG1/BRM-associated factor) and PBAF (polybromo-associated BAF factor), which involves reading of acetylated histone tails by the bromodomain-containing proteins SMARCA2… read more here.
Keywords: smarca pb1; bromodomain inhibitors; role; swi snf ... See more keywords