Identification of small molecule inhibitors targeting the SMARCA2 bromodomain from a high-throughput screening assay
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DOI: 10.1038/aps.2017.188
Abstract: SMARCA2 is a critical catalytic subunit of the switch/sucrose non-fermenting (SWI/SNF) chromatin remodeling complexes. Dysregulation of SMARCA2 is associated with several diseases, including some cancers. SMARCA2 is multi-domain protein containing a bromodomain (BRD) that specifically… read more here.
Keywords: smarca2 brd; targeting smarca2; throughput screening; smarca2 ... See more keywords