Loss of expression of SMARCA4 (BRG1), SMARCA2 (BRM) and SMARCB1 (INI1) in undifferentiated carcinoma of the endometrium is not uncommon and is not always associated with rhabdoid morphology
Sign Up to like & getrecommendations! Published in 2017 at "Histopathology"
DOI: 10.1111/his.13091
Abstract: Abnormalities of SMARCB1 (INI1), which encodes a member of the SWI/SNF pathway, are found in neoplasms with rhabdoid morphology, such as malignant rhabdoid tumour of the kidney and atypical teratoid/rhabdoid tumour of the central nervous… read more here.
Keywords: rhabdoid morphology; morphology; smarca4 brg1; expression smarca4 ... See more keywords
TTF1-positive SMARCA4/BRG1 deficient lung adenocarcinoma.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of pathology and translational medicine"
DOI: 10.4132/jptm.2021.09.16
Abstract: SMARCA4/BRG1-deficient lung adenocarcinoma (SD-LUAD) is being recognized as a distinct subtype based on subtle differences in its clinical, morphological, and immunophenotypic attributes compared to other non-small cell lung carcinomas. We present here a case of… read more here.
Keywords: lung adenocarcinoma; smarca4 brg1; ttf1; brg1 deficient ... See more keywords