Abstract LB-096: SMARCB1-mediated SWI/SNF complex function is essential for enhancer regulation
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DOI: 10.1158/1538-7445.am2017-lb-096
Abstract: The gene encoding SMARCB1 (SNF5/INI1/BAF47), a core subunit of the SWI/SNF (BAF) chromatin remodeling complex, is biallelically inactivated in nearly all rhabdoid tumors (RTs), highly aggressive and lethal cancers of early childhood. RTs are among… read more here.
Keywords: mediated swi; smarcb1 mediated; snf complex; swi snf ... See more keywords