Effects of SMC1A on immune microenvironment and cancer stem cells in colon adenocarcinoma.
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DOI: 10.1002/cam4.5891
Abstract: BACKGROUND Our previous study suggested that SMC1 has significant functions in colorectal cancer (CRC). However, few reports have shown the effects of structural maintenance of chromosomes 1 (SMC1A) on the immune microenvironment and tumor stem… read more here.
Keywords: cell; smc1a; stem cells; cancer ... See more keywords
Phenotypes and Genotypes in Patients with SMC1A-Related Developmental and Epileptic Encephalopathy
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DOI: 10.3390/genes14040852
Abstract: The X-linked SMC1A gene encodes a core subunit of the cohesin complex that plays a pivotal role in genome organization and gene regulation. Pathogenic variants in SMC1A are often dominant-negative and cause Cornelia de Lange… read more here.
Keywords: epileptic encephalopathy; developmental epileptic; phenotypes genotypes; smc1a variants ... See more keywords