Development and Optimization of Vitamin D3 Solid Self-Microemulsifying Drug Delivery System: Investigation of Flowability and Shelf Life
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DOI: 10.1208/s12249-022-02267-z
Abstract: We report herein the design of a solid self-microemulsifying drug delivery system (SMEDDS) of vitamin D3 for augmentation of its solubility and dissolution. The studies employed a 32 full factorial design by employing JMP 13.2.1,… read more here.
Keywords: vit; solid self; smedds; smedds vit ... See more keywords
Cationic Solid SMEDDS of Efavirenz for Improved Oral Delivery: Development by Central Composite Design, In Vitro and In Vivo Evaluation
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DOI: 10.1208/s12249-022-02495-3
Abstract: Efavirenz (EFV) is an anti-HIV drug with high dose and 40% oral bioavailability (BA). The aim was to improve the bioavailability by designing cationic solid SMEDDS. Solubility data, ternary phase diagrams, and central composite design… read more here.
Keywords: solid smedds; smedds; central composite; cationic solid ... See more keywords