Facile synthesis of novel 3,4,5-trisubstituted-1,2,4-triazin-6(1H)-ones via a sequential Ugi–Smiles type/nucleophilic substitution/cyclization reaction
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DOI: 10.1039/c8nj03949f
Abstract: A simple and innovative strategy is described for synthesizing a library of novel 3,4,5-trisubstituted-1,2,4-triazin-6(1H)-one backbones in mild conditions. This approach involves multiple bond-forming events in an Ugi–Smiles type reaction and the post-condensation of the Ugi–Smiles… read more here.
Keywords: novel trisubstituted; smiles type; reaction; trisubstituted triazin ... See more keywords