Immunohistochemical evaluation of Sonic Hedgehog signaling pathway proteins (Shh, Ptch1, Ptch2, Smo, Gli1, Gli2, and Gli3) in sporadic and syndromic odontogenic keratocysts
Sign Up to like & getrecommendations! Published in 2018 at "Clinical Oral Investigations"
DOI: 10.1007/s00784-018-2421-2
Abstract: AimsThe aim of this study was to compare the clinical and demographic features of 62 patients presenting sporadic odontogenic keratocysts (OKCs) or OKCs associated with nevoid basal cell carcinoma syndrome (NBCCS). In conjunction with this,… read more here.
Keywords: shh ptch1; smo; ptch1 ptch2; gli1 ... See more keywords
Molecular modeling study on resistance of WT/D473H SMO to antagonists LDE‐225 and LEQ‐506
Sign Up to like & getrecommendations! Published in 2018 at "Pharmacological Research"
DOI: 10.1016/j.phrs.2017.11.025
Abstract: Graphical abstract The superposition between apo‐WT (pink) and apo‐D473H (palecyan) (a), the hydrogen bonds network and free energy surface of the wild type residue Asp473 (b and d) and the mutant residue His473 (c and… read more here.
Keywords: lde 225; smo; leq 506; resistance ... See more keywords
Gas-Phase Reactivity of Ozone with Lanthanide Ions (Sm+, Nd+) and Their Higher Oxides.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Society for Mass Spectrometry"
DOI: 10.1021/jasms.2c00058
Abstract: The kinetics of SmOn+ (n = 0-2) and NdOn+ (n = 0-2) with O3 are measured using a selected-ion flow tube. Reaction of Nd+ to yield NdO+ + O2 occurs rapidly, with a rate constant… read more here.
Keywords: state; capture limit; cm3 yield; yield ... See more keywords
Improved double‐surface sliding mode observer for flux and speed estimation of induction motors
Sign Up to like & getrecommendations! Published in 2020 at "Iet Electric Power Applications"
DOI: 10.1049/iet-epa.2019.0826
Abstract: This study studies a double-surface sliding-mode observer (DS-SMO) for estimating the flux and speed of induction motors (IMs). The SMO equations are based on an IM model in the stationary reference frame. The DS-SMO is… read more here.
Keywords: double surface; sliding mode; smo; speed ... See more keywords
Polarity and charge redistribution induced emergent interfacial ferromagnetism in non-magnetic LaNiO3/SrMnO3 superlattices
Sign Up to like & getrecommendations! Published in 2020 at "Applied Physics Letters"
DOI: 10.1063/5.0028864
Abstract: Artificial heterostructures composed of strongly correlated oxides can host many up-and-coming phenomena. The interfacial ferromagnetism can be observed at the interface of paramagnetic LaNiO3 (LNO) and G-type antiferromagnetic SrMnO3 (SMO). Through the macroscopic magnetic and… read more here.
Keywords: smo; interfacial ferromagnetism; charge redistribution; exchange ... See more keywords
Genetic alterations conferring resistance to hedgehog inhibitors in basal cell carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Expert Opinion on Drug Safety"
DOI: 10.1080/14740338.2022.2037884
Abstract: With great interest, we read ”Expert opinion on sonidegib efficacy, safety and tolerability” by Villani et al. The authors emphasize the promise of sonidegib and vismodegib, competitive inhibitors of the smoothened (SMO) membrane protein within… read more here.
Keywords: bcc; cell carcinoma; resistance; smo ... See more keywords
Novel Role of Raft-Associated Smoothened (SMO) in AKT Signal Regulation in Diffuse Large B Cell Lymphoma
Sign Up to like & getrecommendations! Published in 2019 at "Blood"
DOI: 10.1182/blood-2019-121847
Abstract: Constitutive PI3K/AKT activation is relevant to multiple aspects of tumor growth and survival in numerous cancers including diffuse large B cell lymphoma (DLBCL). For example, PTEN loss is one of the mechanisms leading to constitutive… read more here.
Keywords: smo; cell; raft associated; raft ... See more keywords
Predictive factors of diagnostic and therapeutic divergence in a nationwide cohort of patients seeking second medical opinion
Sign Up to like & getrecommendations! Published in 2021 at "BMC Health Services Research"
DOI: 10.1186/s12913-021-06936-w
Abstract: Objectives The aim of this study was to describe the profile of patients who sought a second medical opinion (SMO) on their therapeutic or diagnostic strategy using nationwide data from a French physician network dedicated… read more here.
Keywords: smo; second medical; medical opinion; cohort ... See more keywords
Multi-objective lithographic source mask optimization to reduce the uneven impact of polarization aberration at full exposure field.
Sign Up to like & getrecommendations! Published in 2019 at "Optics express"
DOI: 10.1364/oe.27.015604
Abstract: Source and mask optimization (SMO) technology based on vectorial image model is indispensable in immersion lithography process at advanced technology node. Many kinds of algorithms have achieved successes in aspect of fast and robust SMO… read more here.
Keywords: field; exposure field; impact; full exposure ... See more keywords
Desert hedgehog mediates the proliferation of medaka spermatogonia through Smoothened signaling.
Sign Up to like & getrecommendations! Published in 2022 at "Reproduction"
DOI: 10.1530/rep-21-0468
Abstract: Desert hedgehog (DHH) signaling has been reported to be involved in spermatogenesis and the self-renewal of spermatogonial stem cells (SSCs). However, the role of DHH in proliferation of spermatogonia remain to be elucidated. Here we… read more here.
Keywords: smo; spermatogonia; proliferation; desert hedgehog ... See more keywords
Regulation of Smoothened Trafficking and Abundance in Hedgehog Signaling
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.847844
Abstract: The GPCR-family protein Smoothened (Smo) is essential for Hedgehog (Hh) signal transduction in both insects and vertebrates. The regulation of subcellular localization and abundance of Smo is a critical step in Hh signaling. Recent studies… read more here.
Keywords: ubiquitination; hedgehog; trafficking abundance; abundance ... See more keywords