Fluoxetine, an Antidepressant Drug, Inhibited Cigarette Smoke-Induced Pulmonary Inflammation and Apoptosis in Rats
Sign Up to like & getrecommendations! Published in 2017 at "Inflammation"
DOI: 10.1007/s10753-017-0580-y
Abstract: The present study was designed to evaluate the anti-inflammatory effect of fluoxetine (Flu) against cigarette smoke (CS)-induced chronic obstructive pulmonary disease (COPD) in rats. Forty male Sprague-Dawley (SD) rats were randomly assigned to five groups:… read more here.
Keywords: smoke induced; apoptosis; cigarette smoke; flu ... See more keywords
Nebulization of Single-Chain Tissue-Type and Single-Chain Urokinase Plasminogen Activator for Treatment of Inhalational Smoke-Induced Acute Lung Injury.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of drug delivery science and technology"
DOI: 10.1016/j.jddst.2018.04.013
Abstract: Single-chain tissue-type plasminogen activator (sctPA) and single-chain urokinase plasminogen activator (scuPA) have attracted interest as enzymes for the treatment of inhalational smoke-induced acute lung injury (ISALI). In this study, the pulmonary delivery of commercial human… read more here.
Keywords: chain; smoke induced; single chain; plasminogen activator ... See more keywords
Pulmonary delivery of resveratrol-β-cyclodextrin inclusion complexes for the prevention of zinc chloride smoke-induced acute lung injury
Sign Up to like & getrecommendations! Published in 2022 at "Drug Delivery"
DOI: 10.1080/10717544.2022.2048135
Abstract: Abstract Smoke bombs are often used in military/fire training, which can produce a large amount of zinc chloride (ZnCl2) smoke. Inhalation of ZnCl2 smoke usually causes acute lung injury (ALI) that would likely develop to… read more here.
Keywords: smoke; prevention; smoke induced; lung ... See more keywords
Modulation of smoke-induced DNA and microRNA alterations in mouse lung by licofelone, a triple COX-1, COX-2 and 5-LOX inhibitor.
Sign Up to like & getrecommendations! Published in 2019 at "Carcinogenesis"
DOI: 10.1093/carcin/bgz158
Abstract: Chronic inflammation plays a crucial role in the carcinogenesis process and in particular in smoking-related carcinogenesis. Therefore, anti-inflammatory agents provide an interesting perspective in the prevention of smoking-associated cancers. Among nonsteroidal anti-inflammatory drugs (NSAIDs), licofelone… read more here.
Keywords: smoke induced; dna; smoke; licofelone ... See more keywords
Aim2 suppresses cigarette smoke‐induced neutrophil recruitment, neutrophil caspase‐1 activation and anti‐Ly6G‐mediated neutrophil depletion
Sign Up to like & getrecommendations! Published in 2022 at "Immunology and Cell Biology"
DOI: 10.1111/imcb.12537
Abstract: Increased inflammasome responses are strongly implicated in inflammatory diseases; however, their specific roles are incompletely understood. Therefore, we sought to examine the roles of nucleotide‐binding oligomerization domain–like receptor (NLR) family, pyrin domain–containing 3 (NLRP3) and… read more here.
Keywords: cigarette smoke; aim2; smoke induced; anti ly6g ... See more keywords
Efficacy of dexamethasone, salbutamol, and reduced respirable particulate concentration on aerobic capacity in horses with smoke‐induced mild asthma
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Veterinary Internal Medicine"
DOI: 10.1111/jvim.15696
Abstract: Abstract Background Mild asthma in horses decreases racing performance and impairs gas exchange. The efficacy of treatment on performance is unknown. Hypothesis Treatment targeting lung inflammation improves V˙O2peak in horses with mild asthma. Animals Thoroughbred… read more here.
Keywords: smoke induced; mild asthma; treatment; horses smoke ... See more keywords
ROS-Responsive miR-150-5p Downregulation Contributes to Cigarette Smoke-Induced COPD via Targeting IRE1α
Sign Up to like & getrecommendations! Published in 2022 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2022/5695005
Abstract: MicroRNAs (miRNAs) have been reported in human diseases, in which chronic obstructive pulmonary disease (COPD) is included. Herein, we assessed the role along with the possible mechanisms of miR-150-5p in cigarette smoke- (CS-) induced COPD.… read more here.
Keywords: cigarette smoke; copd; smoke induced; induced copd ... See more keywords
Abstract 3947: S100A8/A9-RAGE pathway and chronic airway inflammation in cigarette smoke-induced lung carcinogenesis
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-3947
Abstract: Background: Cigarette smoke-induced chronic airway inflammation increases the risk of lung cancer, and plays a multifaceted role in lung cancer initiation and progression, and RAGE-ligand axis (HMGB1, S100A8/A9) contributes Cigarette smoke-induced persistent and progressive inflammation.… read more here.
Keywords: cigarette smoke; s100a8 rage; rage; smoke induced ... See more keywords
Cigarette smoke induced urocystic epithelial mesenchymal transition via MAPK pathways
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.14456
Abstract: Cigarette smoke has been shown to be a major risk factor for bladder cancer. Epithelial-mesenchymal transition (EMT) is a crucial process in cancer development. The role of MAPK pathways in regulating cigarette smoke-triggered urocystic EMT… read more here.
Keywords: mapk pathways; cigarette smoke; smoke; smoke induced ... See more keywords
Cigarette smoke-induced autophagy: a deadly association?
Sign Up to like & getrecommendations! Published in 2017 at "Journal of thoracic disease"
DOI: 10.21037/jtd.2017.06.132
Abstract: Cigarette smoke, and the mutagen agents it contains, is a universal conveyor of DNA alterations in the pulmonary airway cells, ultimately leading to cancer. In addition, the thousands xenobiotics and pro-oxidant agents contained in smoke… read more here.
Keywords: smoke induced; cigarette smoke; deadly association; autophagy deadly ... See more keywords
Complement component 3 protects human bronchial epithelial cells from cigarette smoke-induced oxidative stress and prevents incessant apoptosis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1035930
Abstract: The complement component 3 (C3) is a pivotal element of the complement system and plays an important role in innate immunity. A previous study showed that intracellular C3 was upregulated in airway epithelial cells (AECs)… read more here.
Keywords: cigarette smoke; stress; apoptosis; oxidative stress ... See more keywords