Positron emission tomography with [18 F]-DPA-714 unveils a smoldering component in most multiple sclerosis lesions which drives disease progression.
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DOI: 10.1002/ana.26657
Abstract: OBJECTIVE To determine the prognostic value of persisting neuroinflammation in multiple sclerosis (MS) lesions, we developed a 18kDa-translocator-protein-PET based classification of each lesion according to innate immune cell content and localization, and assessed the respective… read more here.
Keywords: dpa 714; multiple sclerosis; sclerosis lesions; progression ... See more keywords