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A SMYD3/ITGB6/TGFβ1 Positive Feedback Loop Promotes the Invasion and Adhesion of Ovarian Cancer Spheroids

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Published in 2021 at "Frontiers in Oncology"

DOI: 10.3389/fonc.2021.690618

Abstract: Background Implantation metastasis is the main means of dissemination in ovarian cancer. Our previous studies showed that SET and MYND domain-containing protein 3 (SMYD3) expression was higher in ovarian cancer spheroids than in monolayers. SMYD3… read more here.

Keywords: cancer spheroids; tgf; ovarian cancer; invasion adhesion ... See more keywords