Synthesis and Antitumor Evaluation of Biotin-SN38-Valproic Acid Conjugates
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DOI: 10.3390/molecules28093936
Abstract: Despite the strong anticancer activity of SN38 (7-ethyl-10-hydroxy-camptothecin), the severe side effects and loss of anticancer activity caused by the lack of selectivity to cancer cells and hydrolysis of ring E prevent its clinical application.… read more here.
Keywords: compound; sn38 valproic; biotin; sn38 ... See more keywords