Snakebite envenoming
Sign Up to like & getrecommendations! Published in 2017 at "Nature Reviews Disease Primers"
DOI: 10.1038/nrdp.2017.64
Abstract: The WHO recommends an integrated global strategy to reduce the burden of snakebite envenoming, including educational programmes that detail safe methods for high-risk tasks, better first aid strategies, training of health professionals, research in diagnostics… read more here.
Keywords: snakebite envenoming;
Snakebite envenoming in Brazilian children: clinical aspects, management and outcomes.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of tropical pediatrics"
DOI: 10.1093/tropej/fmad010
Abstract: Snakebite envenoming is currently considered a neglected tropical disease, which affects over 5 million people worldwide, and causes almost 150 000 deaths every year, as well as severe injuries, amputations and other sequelae. Snakebite envenoming in… read more here.
Keywords: brazilian children; management outcomes; snakebite envenoming; clinical aspects ... See more keywords
Paediatric snakebite envenoming: recognition and management of cases
Sign Up to like & getrecommendations! Published in 2020 at "Archives of Disease in Childhood"
DOI: 10.1136/archdischild-2020-319428
Abstract: Snakebite in children can often be severe or potentially fatal, owing to the lower volume of distribution relative to the amount of venom injected, and there is potential for long-term sequelae. In the second of… read more here.
Keywords: management cases; envenoming recognition; management; recognition management ... See more keywords
Recombinant snakebite antivenoms: A cost-competitive solution to a neglected tropical disease?
Sign Up to like & getrecommendations! Published in 2017 at "PLoS Neglected Tropical Diseases"
DOI: 10.1371/journal.pntd.0005361
Abstract: Snakebite envenoming is a major public health burden in tropical parts of the developing world. In sub-Saharan Africa, neglect has led to a scarcity of antivenoms threatening the lives and limbs of snakebite victims. Technological… read more here.
Keywords: snakebite antivenoms; snakebite envenoming; antivenoms cost; recombinant snakebite ... See more keywords
Effect of the time to antivenom administration on recovery from snakebite envenoming-related coagulopathy in French Guiana
Sign Up to like & getrecommendations! Published in 2023 at "PLOS Neglected Tropical Diseases"
DOI: 10.1371/journal.pntd.0011242
Abstract: Background Snakebite (SB) envenoming is an acute emergency requiring an early care delivery. We aimed to search for the time to reach healthcare facilities in various regions of French Guiana (FG) and to assess the… read more here.
Keywords: time; administration; effect time; time antivenom ... See more keywords
Association of a Network of Immunologic Response and Clinical Features With the Functional Recovery From Crotalinae Snakebite Envenoming
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.628113
Abstract: Background The immunologic pathways activated during snakebite envenoming (SBE) are poorly described, and their association with recovery is unclear. The immunologic response in SBE could inform a prognostic model to predict recovery. The purpose of… read more here.
Keywords: recovery; clinical features; post antivenom; functional recovery ... See more keywords
Secretory Phospholipases A2, from Snakebite Envenoming to a Myriad of Inflammation Associated Human Diseases—What Is the Secret of Their Activity?
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24021579
Abstract: Secreted phospholipases of type A2 (sPLA2s) are proteins of 14–16 kDa present in mammals in different forms and at different body sites. They are involved in lipid transformation processes, and consequently in various immune, inflammatory,… read more here.
Keywords: secretory phospholipases; envenoming myriad; phospholipases snakebite; myriad inflammation ... See more keywords
Exploring the Utility of ssDNA Aptamers Directed against Snake Venom Toxins as New Therapeutics for Snakebite Envenoming
Sign Up to like & getrecommendations! Published in 2022 at "Toxins"
DOI: 10.3390/toxins14070469
Abstract: Snakebite is a neglected tropical disease that causes considerable death and disability in the tropical world. Although snakebite can cause a variety of pathologies in victims, haemotoxic effects are particularly common and are typically characterised… read more here.
Keywords: venom; snakebite envenoming; snake venom; utility ... See more keywords
A Review of the Proteomic Profiling of African Viperidae and Elapidae Snake Venoms and Their Antivenom Neutralisation
Sign Up to like & getrecommendations! Published in 2022 at "Toxins"
DOI: 10.3390/toxins14110723
Abstract: Snakebite envenoming is a neglected tropical disease (NTD) that results from the injection of snake venom of a venomous snake into animals and humans. In Africa (mainly in sub-Saharan Africa), over 100,000 envenomings and over… read more here.
Keywords: review; profiling african; snake venoms; neutralisation ... See more keywords
Varespladib in the Treatment of Snakebite Envenoming: Development History and Preclinical Evidence Supporting Advancement to Clinical Trials in Patients Bitten by Venomous Snakes
Sign Up to like & getrecommendations! Published in 2022 at "Toxins"
DOI: 10.3390/toxins14110783
Abstract: The availability of effective, reliably accessible, and affordable treatments for snakebite envenoming is a critical and long unmet medical need. Recently, small, synthetic toxin-specific inhibitors with oral bioavailability used in conjunction with antivenom have been… read more here.
Keywords: envenoming development; clinical trials; snakebite envenoming; treatment ... See more keywords