Analyses des risques concurrents de progression systémique ou au niveau du système nerveux central chez des patients avec CBNPC EGFR muté ayant reçu de l’afatinib dans les études LUX-Lung 3, 6 et 7
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DOI: 10.1016/j.rmr.2018.10.070
Abstract: Introduction Les metastases au niveau du SNC sont une complication connue du CBNPC avance EGFR mute (m+), et les etudes LUX-Lung (LL) evaluant afatinib autorisaient l’inclusion de patients avec metastases cerebrales (MC). LL3, 6 et 7 ont… read more here.
Keywords: afatinib; progression; snc; chez des ... See more keywords
Editorial: Brain Modeling of Neurogenerative Disorders
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DOI: 10.3389/fninf.2022.937790
Abstract: subthalamic nucleus, globus pallidus externa, and SNc. They simulated the molecular pathways involved in cell death of SNc neurons in terms of detailed chemical kinetics. The authors showed that energy deficiencies occurring at cellular and… read more here.
Keywords: modeling neurogenerative; neurogenerative disorders; brain modeling; editorial brain ... See more keywords
A Multi-Scale Computational Model of Levodopa-Induced Toxicity in Parkinson's Disease
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DOI: 10.3389/fnins.2022.797127
Abstract: Parkinson's disease (PD) is caused by the progressive loss of dopaminergic cells in substantia nigra pars compacta (SNc). The root cause of this cell loss in PD is still not decisively elucidated. A recent line… read more here.
Keywords: disease; induced toxicity; model; snc ... See more keywords