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Published in 2024 at "Molecular Carcinogenesis"
DOI: 10.1002/mc.23722
Abstract: DNA methylation, an epigenetic regulatory mechanism dictating gene transcription, plays a critical role in the occurrence and development of cancer. However, the molecular underpinnings of LINC00987 methylation in the regulation of lung adenocarcinoma (LUAD) remain…
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Keywords:
degradation;
linc00987;
phosphorylation;
snd1 ... See more keywords
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Published in 2017 at "Cancer research"
DOI: 10.1158/0008-5472.can-17-0298
Abstract: SND1, a subunit of the miRNA regulatory complex RISC, has been implicated as an oncogene in hepatocellular carcinoma (HCC). In this study, we show that hepatocyte-specific SND1 transgenic mice (Alb/SND1 mice) develop spontaneous HCC with…
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Keywords:
hepatocellular carcinoma;
role snd1;
oncogenic role;
mice ... See more keywords
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Published in 2025 at "Journal of Translational Medicine"
DOI: 10.1186/s12967-025-06762-2
Abstract: Prostate cancer (PCa) is a prevalent cancer and a major cause of cancer-related deaths in men worldwide. Growing evidence indicates that Staphylococcal nuclease and Tudor domain containing 1 (SND1) is a multifunctional protein extensively involved…
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Keywords:
ampk mtor;
cancer;
snd1;
rna ... See more keywords
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Published in 2023 at "Current computer-aided drug design"
DOI: 10.2174/1573409919666230110112356
Abstract: AIMS Cancer is a disease that takes lives of thousands of people each year. There are more than 100 different types of cancers known to man. This fatal disease is one of the leading causes…
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Keywords:
small inhibitors;
identification small;
snd1;
approach ... See more keywords