Snf1/AMPK fine-tunes TORC1 signaling in response to glucose starvation
Sign Up to like & getrecommendations! Published in 2022 at "eLife"
DOI: 10.1101/2022.10.18.512649
Abstract: The AMP-activated protein kinase (AMPK) and the target of rapamycin complex 1 (TORC1) are central kinase modules of two opposing signaling pathways that control eukaryotic cell growth and metabolism in response to the availability of… read more here.
Keywords: glucose starvation; torc1; snf1; growth ... See more keywords
Snf1 cooperates with the CWI MAPK pathway to mediate the degradation of Med13 following oxidative stress
Sign Up to like & getrecommendations! Published in 2018 at "Microbial Cell"
DOI: 10.15698/mic2018.08.641
Abstract: Eukaryotic cells, when faced with unfavorable environmental conditions, mount either pro-survival or pro-death programs. The conserved cyclin C-Cdk8 kinase plays a key role in this decision. Both are members of the Cdk8 kinase module that,… read more here.
Keywords: degradation; cwi mapk; med13; stress ... See more keywords
Conventional and emerging roles of the energy sensor Snf1/AMPK in Saccharomyces cerevisiae
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DOI: 10.15698/mic2018.11.655
Abstract: All proliferating cells need to match metabolism, growth and cell cycle progression with nutrient availability to guarantee cell viability in spite of a changing environment. In yeast, a signaling pathway centered on the effector kinase… read more here.
Keywords: energy; conventional emerging; roles energy; emerging roles ... See more keywords
Fine-Tuning of Energy Levels Regulates SUC2 via a SNF1-Dependent Feedback Loop
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2020.00954
Abstract: Nutrient sensing pathways are playing an important role in cellular response to different energy levels. In budding yeast, Saccharomyces cerevisiae, the sucrose non-fermenting protein kinase complex SNF1 is a master regulator of energy homeostasis. It… read more here.
Keywords: mechanism; energy; feedback; expression ... See more keywords
The polyHIS Tract of Yeast AMPK Coordinates Carbon Metabolism with Iron Availability
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24021368
Abstract: Energy status in all eukaryotic cells is sensed by AMP-kinases. We have previously found that the poly-histidine tract at the N-terminus of S. cerevisiae AMPK (Snf1) inhibits its function in the presence of glucose via… read more here.
Keywords: poly histidine; metabolism; snf1; tract ... See more keywords