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   Articles with "snhg1" as a keyword



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LncRNA SNHG1 alleviates OGD induced injury in BMEC via miR-338/HIF-1α axis

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recommendations! Published in 2019 at "Brain Research"

DOI: 10.1016/j.brainres.2018.11.003

Abstract: BACKGROUND Brain microvascular endothelial cell (BMEC) is an important therapeutic target for the inhibition of brain vascular dysfunction in ischemic stroke. Expression of long non-coding RNA SNHG1 is reportedly upregulated in BMEC after OGD. The… read more here.

Keywords: snhg1; ogd induced; bmec; induced injury ... See more keywords

FtMt promotes glioma tumorigenesis and angiogenesis via lncRNA SNHG1/miR-9-5p axis.

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recommendations! Published in 2020 at "Cellular signalling"

DOI: 10.1016/j.cellsig.2020.109749

Abstract: OBJECTIVE This study is to investigate the effects and the mechanisms of mitochondrial ferritin (FtMt) on the glioma tumorigenesis and angiogenesis. METHODS FtMt expression was detected in glioma tissues and cells as well as in… read more here.

Keywords: glioma tumorigenesis; tumorigenesis angiogenesis; ftmt; snhg1 ... See more keywords
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LncRNA SNHG1 promotes &agr;‐synuclein aggregation and toxicity by targeting miR‐15b‐5p to activate SIAH1 in human neuroblastoma SH‐SY5Y cells

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recommendations! Published in 2018 at "Neurotoxicology"

DOI: 10.1016/j.neuro.2017.12.001

Abstract: HighlightsSNHG1 is upregulated and miR‐15b‐5p is downregulated in PD.SIAH1 promotes &agr;‐synuclein aggregation and toxicity.SIAH1 is a target gene of miR‐15b‐5p.SNHG1 is able to directly bind to miR‐15‐5p and represses miR‐15‐5p expression.SNHG1 promotes &agr;‐synuclein aggregation and… read more here.

Keywords: synuclein aggregation; snhg1; mir 15b; siah1 ... See more keywords
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Long non-coding RNA SNHG1 protects human AC16 cardiomyocytes from doxorubicin toxicity by regulating miR-195/Bcl-2 axis

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recommendations! Published in 2019 at "Bioscience Reports"

DOI: 10.1042/bsr20191050

Abstract: Doxorubicin (DOX) is a highly effective anti-tumor drug, but its cardiotoxicity largely restricts its clinical application. The present study was designed to explore whether in vitro DOX toxicity in AC16 cardiomyocytes can be regulated by… read more here.

Keywords: mir 195; snhg1; toxicity; 195 bcl ... See more keywords
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LncRNA-SNHG1 promotes paclitaxel resistance of gastric cancer cells through modulating the miR-216b-5p-hexokianse 2 axis.

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recommendations! Published in 2022 at "Journal of chemotherapy"

DOI: 10.1080/1120009x.2022.2157618

Abstract: Gastric cancer (GC) is one of the most malignant tumors with high incidence and poor prognosis. Currently, the combination of surgery with chemo- or radiotherapy is widely applied therapeutic strategy against GC. However, development of… read more here.

Keywords: snhg1; resistance; mir 216b; gastric cancer ... See more keywords
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Aberrant Circulating SNHG1 Serves as a Biomarker to Distinguish Acute Myocardial Infarction and Construction of a Risk Model for Secondary Heart Failure

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recommendations! Published in 2022 at "Journal of Cardiovascular Pharmacology"

DOI: 10.1097/fjc.0000000000001298

Abstract: Abstract: Acute myocardial infarction (AMI) is a severe condition observed in patients with coronary heart disease, and heart failure (HF) often occurs after AMI. This study aimed to evaluate the clinical significance of long noncoding… read more here.

Keywords: risk model; snhg1; ami; heart ... See more keywords
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Upregulation of lncRNA SNHG1 is associated with metastasis and poor prognosis in cancers

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recommendations! Published in 2019 at "Medicine"

DOI: 10.1097/md.0000000000015196

Abstract: Background: Accumulating evidence suggested that the expression level of long noncoding RNA small nucleolar RNA host gene 1 (lncRNA SNHG1) was upregulated in various cancers, and high expression of SNHG1 was associated with metastasis and… read more here.

Keywords: expression; snhg1; metastasis; lncrna snhg1 ... See more keywords
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LncRNA SNHG1 modulates adipogenic differentiation of BMSCs by promoting DNMT1 mediated Opg hypermethylation via interacting with PTBP1

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recommendations! Published in 2021 at "Journal of Cellular and Molecular Medicine"

DOI: 10.1111/jcmm.16982

Abstract: Recent evidence indicates that the abnormal differentiation of bone marrow‐derived mesenchymal stem cells (BMSCs) plays a pivotal role in the pathogenesis of osteoporosis. LncRNA SNHG1 has been found to be associated with the differentiation ability… read more here.

Keywords: differentiation; expression; bmscs; adipogenic differentiation ... See more keywords
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SNHG1, a KLF4-upregulated gene, promotes glioma cell survival and tumorigenesis under endoplasmic reticulum stress by upregulating BIRC3 expression.

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recommendations! Published in 2023 at "Journal of cellular and molecular medicine"

DOI: 10.1111/jcmm.17779

Abstract: Increasing evidence indicates that long noncoding RNAs (lncRNAs) play crucial roles in the resistance to endoplasmic reticulum (ER) stress in many cancers. However, ER stress-regulated lncRNAs are still unknown in glioma. In the present study,… read more here.

Keywords: endoplasmic reticulum; birc3 expression; stress; snhg1 ... See more keywords
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Hypoxic Breast Cancer Cell-Derived Exosomal SNHG1 Promotes Breast Cancer Growth and Angiogenesis via Regulating miR-216b-5p/JAK2 Axis

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recommendations! Published in 2022 at "Cancer Management and Research"

DOI: 10.2147/cmar.s327621

Abstract: Background Hypoxia is an important process that involved in the tumor microenvironment. In addition, hypoxic tumor cell-derived exosomes could promote tumor growth and angiogenesis. Thus, we aimed to investigate whether exosomes could regulate tumor development… read more here.

Keywords: hypoxic breast; breast cancer; cancer; snhg1 ... See more keywords
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Tanreqing Injection Attenuates Macrophage Activation and the Inflammatory Response via the lncRNA-SNHG1/HMGB1 Axis in Lipopolysaccharide-Induced Acute Lung Injury

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recommendations! Published in 2022 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2022.820718

Abstract: The etiology of acute lung injury (ALI) is not clear, and the treatment of ALI presents a great challenge. This study aimed to investigate the pathogenesis and potential therapeutic targets of ALI and to define… read more here.

Keywords: macrophage activation; acute lung; snhg1; lncrna snhg1 ... See more keywords