Discovering Genetic Factors for psoriasis through exhaustively searching for significant second order SNP-SNP interactions
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DOI: 10.1038/s41598-018-33493-w
Abstract: In this paper, we aim at discovering genetic factors of psoriasis through searching for statistically significant SNP-SNP interactions exhaustively from two real psoriasis genome-wide association study datasets (phs000019.v1.p1 and phs000982.v1.p1) downloaded from the database of… read more here.
Keywords: genetic factors; discovering genetic; snp snp; snp ... See more keywords
ELSSI: parallel SNP-SNP interactions detection by ensemble multi-type detectors
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DOI: 10.1093/bib/bbac213
Abstract: With the development of high-throughput genotyping technology, single nucleotide polymorphism (SNP)-SNP interactions (SSIs) detection has become an essential way for understanding disease susceptibility. Various methods have been proposed to detect SSIs. However, given the disease… read more here.
Keywords: snp snp; ssis; snp; multi type ... See more keywords
A Review on Methods for Detecting SNP Interactions in High-Dimensional Genomic Data
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DOI: 10.1109/tcbb.2016.2635125
Abstract: In this era of genome-wide association studies (GWAS), the quest for understanding the genetic architecture of complex diseases is rapidly increasing more than ever before. The development of high throughput genotyping and next generation sequencing… read more here.
Keywords: high dimensional; methods detecting; interactions high; review methods ... See more keywords
Detecting Disease-Associated SNP-SNP Interactions Using Progressive Screening Memetic Algorithm
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DOI: 10.1109/tcbb.2020.3019256
Abstract: Hundreds of thousands of single nucleotide polymorphisms (SNPs)are currently available for genome-wide association study (GWAS). Detecting disease-associated SNP-SNP interactions is considered an important way to capture the underlying genetic causes of complex diseases. In the… read more here.
Keywords: snp snp; detecting disease; snp interactions; associated snp ... See more keywords