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Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.845498
Abstract: Background: Monogenic familial hypercholesterolaemia (FH) is an autosomal dominant disorder characterised by elevated low-density lipoprotein cholesterol (LDL-C) concentrations due to monogenic mutations in LDLR, APOB, PCSK9, and APOE. Some mutation-negative patients have a polygenic cause…
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Keywords:
ldl concentrations;
snp score;
hypercholesterolaemia;
ethnic groups ... See more keywords