Reference‐free discovery of nuclear SNPs permits accurate, sensitive identification of Carya (hickory) species and hybrids
Sign Up to like & getrecommendations! Published in 2022 at "Applications in Plant Sciences"
DOI: 10.1002/aps3.11455
Abstract: Abstract Premise DNA‐based species identification is critical when morphological identification is restricted, but DNA‐based identification pipelines typically rely on the ability to compare homologous sequence data across species. Because many clades lack robust genomic resources,… read more here.
Keywords: identification; free discovery; snps; discovery nuclear ... See more keywords
Association of asthma genetic variants with asthma‐associated traits reveals molecular pathways of eosinophilic asthma
Sign Up to like & getrecommendations! Published in 2022 at "Clinical and Translational Allergy"
DOI: 10.1002/clt2.12239
Abstract: Abstract Introduction Asthma is a complex, polygenic, heterogenous inflammatory disease. Recently, we generated a list of 128 independent single nucleotide polymorphisms (SNPs) associated with asthma in genome‐wide association studies. However, it is unknown if asthma… read more here.
Keywords: snps associated; asthma; snps; asthma associated ... See more keywords
Comparative assessment of range‐wide patterns of genetic diversity and structure with SNPs and microsatellites: A case study with Iberian amphibians
Sign Up to like & getrecommendations! Published in 2020 at "Ecology and Evolution"
DOI: 10.1002/ece3.6670
Abstract: Abstract Reduced representation genome sequencing has popularized the application of single nucleotide polymorphisms (SNPs) to address evolutionary and conservation questions in nonmodel organisms. Patterns of genetic structure and diversity based on SNPs often diverge from… read more here.
Keywords: snps; diversity; genetic diversity; patterns genetic ... See more keywords
Relative impact of indels versus SNPs on complex disease
Sign Up to like & getrecommendations! Published in 2019 at "Genetic Epidemiology"
DOI: 10.1002/gepi.22175
Abstract: It is unclear whether insertions and deletions (indels) are more likely to influence complex traits than abundant single‐nucleotide polymorphisms (SNPs). We sought to understand which category of variation is more likely to impact health. Using… read more here.
Keywords: snps; relative impact; versus snps; impact ... See more keywords
Novel approach to functional SNPs discovery from genome‐wide data reveals promising variants for colon cancer risk
Sign Up to like & getrecommendations! Published in 2018 at "Human Mutation"
DOI: 10.1002/humu.23425
Abstract: In the majority of colorectal cancer (CRC) cases, the genetic basis of predisposition remains unexplained. The goal of the study was to assess the regulatory SNPs (rSNPs) in the human genome and to reveal СRC… read more here.
Keywords: genome wide; risk; snps; novel approach ... See more keywords
Identification of miRSNPs associated with the risk of multiple myeloma
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DOI: 10.1002/ijc.30465
Abstract: Multiple myeloma (MM) is a malignancy of plasma cells usually infiltrating the bone marrow, associated with the production of a monoclonal immunoglobulin (M protein) which can be detected in the blood and/or urine. Multiple lines… read more here.
Keywords: associated risk; risk; snps; multiple myeloma ... See more keywords
Meta‐Analysis of Genome‐Wide Association Studies Identifies Three Loci Associated With Stiffness Index of the Calcaneus
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Bone and Mineral Research"
DOI: 10.1002/jbmr.3703
Abstract: The stiffness index (SI) from quantitative ultrasound measurements is a good indicator of BMD and may be used to predict the risk of osteoporotic fracture. We conducted a genomewide association study (GWAS) for SI using… read more here.
Keywords: snps; meta analysis; analysis; three loci ... See more keywords
In silico evidence of high frequency of miRNA‐related SNPs in Esophageal Squamous Cell Carcinoma
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.29012
Abstract: Esophageal squamous cell carcinoma (ESCC) is the dominant histological type of esophageal cancer significantly reported in developing nations. There is an increasing evidence suggesting that single nucleotide polymorphisms (SNPs) in the untranslated regions of genes… read more here.
Keywords: snps; squamous cell; mir snps; evidence ... See more keywords
Association of single nucleotide polymorphisms with dyslipidemia and risk of metabolic disorders in the State of Qatar.
Sign Up to like & getrecommendations! Published in 2023 at "Molecular genetics & genomic medicine"
DOI: 10.1002/mgg3.2178
Abstract: BACKGROUND Dyslipidemia is recognized as one of the risk factors of cardiovascular diseases (CVDs), type 2 diabetes mellitus (T2DM), and non-alcoholic fatty liver disease (NAFLD). OBJECTIVE The study aimed to investigate the association between selected… read more here.
Keywords: nucleotide polymorphisms; single nucleotide; snps; risk ... See more keywords
An alternate workflow for preparing Precision ID Ancestry and Identity Panel libraries for Illumina sequencing
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Legal Medicine"
DOI: 10.1007/s00414-021-02549-4
Abstract: Single nucleotide polymorphisms (SNPs) are well-established for forensic applications. Although they are not compatible with existing criminal databases, they offer some advantages over short tandem repeat (STR) markers including smaller amplicons, no stutter artifacts, and… read more here.
Keywords: precision ancestry; snps; ancestry identity; ancestry ... See more keywords
Integrative genomic analysis predicts novel functional enhancer-SNPs for bone mineral density
Sign Up to like & getrecommendations! Published in 2019 at "Human Genetics"
DOI: 10.1007/s00439-019-01971-4
Abstract: Osteoporosis is a skeletal disorder characterized by low bone mineral density (BMD) and deterioration of bone microarchitecture. To identify novel genetic loci underlying osteoporosis, an effective strategy is to focus on scanning of variants with… read more here.
Keywords: bone mineral; snps; enhancer snps; mineral density ... See more keywords