Association of asthma genetic variants with asthma‐associated traits reveals molecular pathways of eosinophilic asthma
Sign Up to like & getrecommendations! Published in 2022 at "Clinical and Translational Allergy"
DOI: 10.1002/clt2.12239
Abstract: Abstract Introduction Asthma is a complex, polygenic, heterogenous inflammatory disease. Recently, we generated a list of 128 independent single nucleotide polymorphisms (SNPs) associated with asthma in genome‐wide association studies. However, it is unknown if asthma… read more here.
Keywords: snps associated; asthma; snps; asthma associated ... See more keywords
A renal genetic risk score (GRS) is associated with kidney dysfunction in people with type 2 diabetes.
Sign Up to like & getrecommendations! Published in 2018 at "Diabetes research and clinical practice"
DOI: 10.1016/j.diabres.2018.08.013
Abstract: This study aims to investigate whether renal and cardiovascular phenotypes in Italian patients with type 2 diabetes (T2D) could be influenced by a number of disease risk SNPs recently found in genome-wide association studies (GWAS).… read more here.
Keywords: risk; snps associated; associated kidney; type diabetes ... See more keywords
Signatures of natural selection in a foundation tree along Mediterranean climatic gradients
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Ecology"
DOI: 10.1111/mec.16351
Abstract: Temperature and precipitation regimes are rapidly changing, resulting in forest dieback and extinction events, particularly in Mediterranean‐type climates (MTC). Forest management that enhance forests’ resilience is urgently required, however adaptation to climates in heterogeneous landscapes… read more here.
Keywords: temperature precipitation; signatures natural; snps associated; selection ... See more keywords
Single-nucleotide polymorphisms (SNPs) associated with outcomes in patients with localized and metastatic renal cell carcinoma (RCC).
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2017.35.6_suppl.437
Abstract: 437Background: Despite major advances in the knowledge of the molecular basis of RCC, prognosis is still defined using clinical and pathological parameters. Moreover, no valid predictive biomarkers exist to help us selecting the best treatment… read more here.
Keywords: polymorphisms snps; snps associated; snps; nucleotide polymorphisms ... See more keywords
Identifying Pleiotropic SNPs Associated With Femoral Neck and Heel Bone Mineral Density
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2020.00772
Abstract: Background Genome-wide association studies (GWASs) routinely identify loci associated with risk factors for osteoporosis. However, GWASs with relatively small sample sizes still lack sufficient power to ascertain the majority of genetic variants with small to… read more here.
Keywords: snps associated; putative causal; bmd; fnk bmd ... See more keywords
Overview of SNPs Associated with Trans Fat Content in Cow’s Milk
Sign Up to like & getrecommendations! Published in 2023 at "Agriculture"
DOI: 10.3390/agriculture13061151
Abstract: Lipids consumed with milk derivatives are one of the main parts of the human diet. Trans fatty acids in milk are causing a debate about their impact on the incidence of cardiovascular disease, pathological abnormalities,… read more here.
Keywords: trans fatty; snps associated; cow milk; milk ... See more keywords
Bulked Segregant Analysis and Association Analysis Identified the Polymorphisms Related to the Intermuscular Bones in Common Carp (Cyprinus carpio)
Sign Up to like & getrecommendations! Published in 2022 at "Biology"
DOI: 10.3390/biology11030477
Abstract: Simple Summary Many widely cultured freshwater fish species, such as common carp, belong to the Cyprinidae family. However, most cyprinids have numerous and complex intermuscular bones (IBs), resulting in an adverse effect on cyprinid fish… read more here.
Keywords: analysis; bulked segregant; common carp; snps associated ... See more keywords
Suitability of GWAS as a Tool to Discover SNPs Associated with Tick Resistance in Cattle: A Review
Sign Up to like & getrecommendations! Published in 2021 at "Pathogens"
DOI: 10.3390/pathogens10121604
Abstract: Understanding the biological mechanisms underlying tick resistance in cattle holds the potential to facilitate genetic improvement through selective breeding. Genome wide association studies (GWAS) are popular in research on unraveling genetic determinants underlying complex traits… read more here.
Keywords: tick resistance; resistance; snps associated; resistance cattle ... See more keywords