Association of SNPs in genes encoding zinc transporters on blood zinc levels in humans.
Sign Up to like & getrecommendations! Published in 2018 at "Legal medicine"
DOI: 10.1016/j.legalmed.2017.10.009
Abstract: Zinc homeostasis in cells depends on zinc transporters, which are divided into 2 families: ZnT (SLC30A) and ZIP (SLC39A). In this study, we examined the effect of 20 single nucleotide polymorphisms (SNPs) in 10 genes… read more here.
Keywords: zinc; blood zinc; genes encoding; zinc transporters ... See more keywords
A telescope GWAS analysis strategy, based on SNPs-genes-pathways ensamble and on multivariate algorithms, to characterize late onset Alzheimer’s disease
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-67699-8
Abstract: Genome–wide association studies (GWAS) have revealed a plethora of putative susceptibility genes for Alzheimer’s disease (AD), with the sole exception of APOE gene unequivocally validated in independent study. Considering that the etiology of complex diseases… read more here.
Keywords: genes pathways; alzheimer disease; analysis strategy; gwas analysis ... See more keywords
Assessment of the Potential Role of Selected Single Nucleotide Polymorphisms (SNPs) of Genes Related to the Functioning of Regulatory T Cells in the Pathogenesis of Psoriasis
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24076061
Abstract: Recent studies have indicated a key role of the impaired suppressive capacity of regulatory T cells (Tregs) in psoriasis (PsO) pathogenesis. However, the genetic background of Treg dysfunctions remains unknown. The aim of this study… read more here.
Keywords: regulatory cells; role; snps genes; pathogenesis ... See more keywords