A prometastatic splicing program regulated by SNRPA1 interactions with structured RNA elements
Sign Up to like & getrecommendations! Published in 2021 at "Science"
DOI: 10.1126/science.abc7531
Abstract: Characterizing a cancer spliceosome Cells undergo many genomic changes as they progress toward metastatic cancer. One aspect of this change is to RNA expression and splicing isoforms, but how these differences affect tumor progression is… read more here.
Keywords: rna structural; breast cancer; cancer; snrpa1 ... See more keywords
Elevated SNRPA1, as a Promising Predictor Reflecting Severe Clinical Outcome via Effecting Tumor Immunity for ccRCC, Is Related to Cell Invasion, Metastasis, and Sunitinib Sensitivity
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.842069
Abstract: Clear cell renal cell carcinoma (ccRCC) is the most common subtype of renal carcinoma and is associated with poor prognosis and notorious for its immune dysfunction characteristic. SNRPA1 is a spliceosome component responsible for processing… read more here.
Keywords: cell; snrpa1; tumor immunity; ccrcc ... See more keywords