SNX27–Retromer directly binds ESCPE-1 to transfer cargo proteins during endosomal recycling
Sign Up to like & getrecommendations! Published in 2022 at "PLoS Biology"
DOI: 10.1371/journal.pbio.3001601
Abstract: Coat complexes coordinate cargo recognition through cargo adaptors with biogenesis of transport carriers during integral membrane protein trafficking. Here, we combine biochemical, structural, and cellular analyses to establish the mechanistic basis through which SNX27–Retromer, a… read more here.
Keywords: retromer; cargo proteins; snx27 retromer; membrane ... See more keywords
Toward Understanding the Molecular Role of SNX27/Retromer in Human Health and Disease
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2021.642378
Abstract: Aberrations in membrane trafficking pathways have profound effects in cellular dynamics of cellular sorting processes and can drive severe physiological outcomes. Sorting nexin 27 (SNX27) is a metazoan-specific sorting nexin protein from the PX-FERM domain… read more here.
Keywords: snx27 retromer; toward understanding; disease; snx27 ... See more keywords