Articles with "snx5" as a keyword



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Upregulation of SNX5 predicts poor prognosis and promotes hepatocellular carcinoma progression by modulating the EGFR-ERK1/2 signaling pathway

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Published in 2019 at "Oncogene"

DOI: 10.1038/s41388-019-1131-9

Abstract: Endocytosis is an essential component of cell motility, which facilitates the malignant behavior of cancer. Sorting nexin (SNX) family members are associated with tumor progression. However, the role and mechanism of SNX5 in hepatocellular carcinoma… read more here.

Keywords: hcc; snx5; cell proliferation; progression ... See more keywords
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The association of lipid transfer protein VPS13A with endosomes is mediated by sorting nexin SNX5

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Published in 2023 at "Life Science Alliance"

DOI: 10.26508/lsa.202201852

Abstract: Binding of sorting nexin SNX5 to the VAB domain of VPS13A mediates its recruitment to membrane contact sites between SNX5-containing endosomal membranes, mitochondria, and ER. Human VPS13 proteins are implicated in severe neurological diseases. These… read more here.

Keywords: nexin snx5; snx5; sorting nexin; vps13a ... See more keywords