Loss of schizophrenia-related miR-501-3p in mice impairs sociability and memory by enhancing mGluR5-mediated glutamatergic transmission
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DOI: 10.1126/sciadv.abn7357
Abstract: Schizophrenia is a polygenetic disease, the heterogeneity of which is likely complicated by epigenetic modifications yet to be elucidated. Here, we performed transcriptomic analysis of peripheral blood RNA from monozygotic twins discordant for schizophrenia and… read more here.
Keywords: glutamatergic transmission; loss; sociability memory; mir 501 ... See more keywords