Behavioral Intervention for Social Challenges in Children and Adolescents: A Systematic Review and Meta-analysis.
Sign Up to like & getrecommendations! Published in 2021 at "JAMA pediatrics"
DOI: 10.1001/jamapediatrics.2021.3982
Abstract: Importance Social deficits are a common and disabling feature of many pediatric disorders; however, whether behavioral interventions are associated with benefits for children and adolescents with social deficits is poorly understood. Objective To assess whether… read more here.
Keywords: intervention; social cognition; social deficits; control ... See more keywords
Neural Circuits Regulating Social Behavior: Highlighting the Causal Contribution of the Lateral Habenula
Sign Up to like & getrecommendations! Published in 2018 at "Biological Psychiatry"
DOI: 10.1016/j.biopsych.2018.01.022
Abstract: Social dysfunctions belong to the core features of several psychiatric disorders, including autism spectrum disorder, personality disorders, and schizophrenia. In schizophrenia, these social deficits often persist after standard treatment and contribute to chronic functional disability… read more here.
Keywords: social deficits; social behavior; activation; neural circuits ... See more keywords
GABAergic malfunction in the anterior cingulate cortex underlying maternal immune activation-induced social deficits
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Neuroimmunology"
DOI: 10.1016/j.jneuroim.2018.06.006
Abstract: Social deficits are one of the major symptoms of psychiatric disorders, including autism spectrum disorders (ASDs) and schizophrenia. However, the underlying mechanism remains ill-defined. Here, we focused on the anterior cingulate cortex (ACC), a brain… read more here.
Keywords: immune activation; maternal immune; social deficits; cingulate cortex ... See more keywords
Vitamin B6 deficiency hyperactivates the noradrenergic system, leading to social deficits and cognitive impairment
Sign Up to like & getrecommendations! Published in 2021 at "Translational Psychiatry"
DOI: 10.1038/s41398-021-01381-z
Abstract: We have reported that a subpopulation of patients with schizophrenia have lower levels of vitamin B 6 (VB6) in peripheral blood than do healthy controls. In a previous study, we found that VB6 level was… read more here.
Keywords: social deficits; vb6 mice; mice; deficiency ... See more keywords
Oxytocin Receptor Polymorphisms are Differentially Associated with Social Abilities across Neurodevelopmental Disorders
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-10821-0
Abstract: Oxytocin is a pituitary neuropeptide that affects social behaviour. Single nucleotide polymorphisms (SNPs) in the oxytocin receptor gene (OXTR) have been shown to explain some variability in social abilities in control populations. Whether these variants… read more here.
Keywords: social deficits; receptor polymorphisms; social abilities; oxytocin receptor ... See more keywords
Prenatal Progestin Exposure-Mediated Oxytocin Suppression Contributes to Social Deficits in Mouse Offspring
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2022.840398
Abstract: Epidemiological studies have shown that maternal hormone exposure is associated with autism spectrum disorders (ASD). The hormone oxytocin (OXT) is a central nervous neuropeptide that plays an important role in social behaviors as well as… read more here.
Keywords: mouse offspring; deficits mouse; progestin exposure; exposure mediated ... See more keywords
Retinoic Acid Supplementation Rescues the Social Deficits in Fmr1 Knockout Mice
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.928393
Abstract: Autism spectrum disorder (ASD) is a heritable neurodevelopmental disorder with the underlying etiology yet incompletely understood and no cure treatment. Patients of fragile X syndrome (FXS) also manifest symptoms, e.g. deficits in social behaviors, that… read more here.
Keywords: supplementation; rescues social; supplementation rescues; retinoic acid ... See more keywords