microRNA‐30a inhibits the liver cell proliferation and promotes cell apoptosis through the JAK/STAT signaling pathway by targeting SOCS‐1 in rats with sepsis
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.28410
Abstract: Sepsis is a systemic inflammatory response that may be induced by trauma, infection, surgery, and burns. With the aim of discovering novel treatment targets for sepsis, this current study was conducted to investigate the effect… read more here.
Keywords: cell proliferation; mir 30a; socs; liver cell ... See more keywords
Cytokine signaling pathway in cystic fibrosis: expression of SOCS and STATs genes in different clinical phenotypes of the disease.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular and cellular biochemistry"
DOI: 10.1007/s11010-021-04051-2
Abstract: This was an observational cross-sectional study which was done to assess the expression profile of STATs and SOCS genes in cystic fibrosis. The mRNA was isolated from peripheral blood mononuclear cells of CF patients in… read more here.
Keywords: cystic fibrosis; cytokine signaling; socs; signaling pathway ... See more keywords
The E3 ubiquitin ligase SOCS-7 reverses immunosuppression via Shc1 signaling in hepatocellular carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Laboratory Investigation"
DOI: 10.1038/s41374-022-00727-5
Abstract: Hepatocellular carcinoma (HCC) is one of the most common primary liver malignancies and is the third leading cause of tumor-related mortality worldwide. Despite advances in HCC treatment, diagnosis at the later stages, and the complex… read more here.
Keywords: socs; hcc; hepatocellular carcinoma; immunosuppression ... See more keywords
CpG Island Methylation of Suppressor of Cytokine Signaling-1 Gene Induced by HCV Is Associated With HCV-Related Hepatocellular Carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.679593
Abstract: Suppressor of cytokine signaling 1 (SOCS-1) is implicated in both virus infection and carcinogenesis. This study investigated the role of HCV infection on SOCS-1 in normal and HCV-infected tissues and revealed a possible mechanism underlying… read more here.
Keywords: methylation; infection; expression; hcv ... See more keywords
Behavioral Monitoring of Sexual Offenders Against Children in Virtual Risk Situations: A Feasibility Study
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Psychology"
DOI: 10.3389/fpsyg.2018.00224
Abstract: The decision about unsupervised privileges for sexual offenders against children (SOC) is one of the most difficult decisions for practitioners in forensic high-security hospitals. Facing the possible consequences of the decision for the society, a… read more here.
Keywords: risk; behavioral monitoring; risk situations; socs ... See more keywords
LncRNA MALAT1 Participates in Protection of High-Molecular-Weight Hyaluronan against Smoke-Induced Acute Lung Injury by Upregulation of SOCS-1
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27134128
Abstract: Smoke-induced acute lung injury (ALI) is a grievous disease with high mortality. Despite advances in medical intervention, no drug has yet been approved by the Food and Drug Administration (FDA) for ALI. In this study,… read more here.
Keywords: smoke; smoke induced; lung; malat1 ... See more keywords