MerTK negatively regulates Staphylococcus aureus induced inflammatory response via SOCS1/SOCS3 and Mal.
Sign Up to like & getrecommendations! Published in 2020 at "Immunobiology"
DOI: 10.1016/j.imbio.2020.151960
Abstract: OBJECTIVE Staphylococcus aureus (S. aureus), one of Gram-positive pathogen, is frequently associated with acute lung inflammation. The central feature of S. aureus acute lung inflammation are pulmonary dysfunctioning and impeded host defence response, which cause… read more here.
Keywords: socs1 socs3; staphylococcus aureus; aureus induced; mertk ... See more keywords
SOCS3 Is Upregulated and Targeted by miR30a-5p in Allergic Rhinitis
Sign Up to like & getrecommendations! Published in 2018 at "International Archives of Allergy and Immunology"
DOI: 10.1159/000486857
Abstract: Background: Suppressor of cytokine signaling 1 (SOCS1) and SOCS3 play important roles in T helper cell differentiation, which is involved with the pathologic mechanisms of allergic rhinitis (AR). The aim of this study was to… read more here.
Keywords: allergic rhinitis; targeted mir30a; socs3; mir30a ... See more keywords
Prognostic significance of SOCS1 and SOCS3 tumor suppressors and oncogenic signaling pathway genes in hepatocellular carcinoma
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DOI: 10.1186/s12885-020-07285-3
Abstract: Background SOCS1 and SOCS3 genes are considered tumor suppressors in hepatocellular carcinoma (HCC) due to frequent epigenetic repression. Consistent with this notion, mice lacking SOCS1 or SOCS3 show increased susceptibility to diethylnitrosamine (DEN)-induced HCC. As… read more here.
Keywords: socs1; hcc; pathway genes; oncogenic signaling ... See more keywords
Murine cytomegalovirus infection of mouse macrophages stimulates early expression of suppressor of cytokine signaling (SOCS)1 and SOCS3
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DOI: 10.1371/journal.pone.0171812
Abstract: Human cytomegalovirus (HCMV) is a species-specific β-herpesvirus that infects for life up to 80% of the world’s population and causes severe morbidity in at-risk immunocompromised populations. Suppressors of cytokine signaling (SOCS)1 and SOCS3 are host… read more here.
Keywords: socs3; mcmv; infection; expression ... See more keywords
Correlative analyses of the expression levels of PIAS3, p-SHP2, SOCS1 and SOCS3 with STAT3 activation in human astrocytomas.
Sign Up to like & getrecommendations! Published in 2017 at "Molecular medicine reports"
DOI: 10.3892/mmr.2016.6079
Abstract: The importance of signal transducer and activator of transcription 3 (STAT3) signaling in the growth and survival of glioblastoma cells has been well documented, while the reasons leading to STAT3 activation remains to be elucidated. Suppressors… read more here.
Keywords: stat3 activation; socs1 socs3; expression levels;