miR-3648 promotes lung adenocarcinoma-genesis by inhibiting SOCS2 (suppressor of cytokine signaling 2)
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DOI: 10.1080/21655979.2021.2017577
Abstract: ABSTRACT Lung adenocarcinoma (LUAD) is the most common histologic subtype of lung cancer and is associated with high morbidity and mortality. We aimed to study the effects of microRNA-3648 (miR-3648) on LUAD by inhibiting its… read more here.
Keywords: socs2; suppressor cytokine; mir; mir 3648 ... See more keywords
CircNOL10 suppresses breast cancer progression by sponging miR-767-5p to regulate SOCS2/JAK/STAT signaling
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DOI: 10.1186/s12929-020-00697-0
Abstract: Background Circular RNAs (circRNAs) have caught increasing attentions and interests for their important involvement in cancer initiation and progression. This study aims to investigate the biological functions of circNOL10 and its potential molecular mechanisms in… read more here.
Keywords: circnol10; socs2; breast cancer; mir 767 ... See more keywords
MiR-532-3p inhibited the methylation of SOCS2 to suppress the progression of PC by targeting DNMT3A
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DOI: 10.26508/lsa.202201703
Abstract: MiR-532-3p has a low expression in pancreatic cancer, but its overexpression can inhibit the tumor progression via DNMT3A-dependent inhibition of SOCS2 methylation. Pancreatic cancer (PC) is one of the deadliest malignancies, with poor diagnosis and… read more here.
Keywords: methylation socs2; socs2; overexpression; mir 532 ... See more keywords