SOCS6 Promotes Mitochondrial Fission and Cardiomyocyte Apoptosis and Is Negatively Regulated by Quaking-Mediated miR-19b
Sign Up to like & getrecommendations! Published in 2022 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2022/1121323
Abstract: Background Mitochondrial dysfunction and abnormal mitochondrial fission have been implicated in the complications associated with I/R injury as cardiomyocytes are abundant in mitochondria. SOCS6 is known to participate in mitochondrial fragmentation, but its exact involvement… read more here.
Keywords: mitochondrial fission; apoptosis; mir 19b; socs6 ... See more keywords
Down-regulation of SOCS6: an unfavorable prognostic factor for gastrointestinal stromal tumor proven by survival analysis
Sign Up to like & getrecommendations! Published in 2021 at "Diagnostic Pathology"
DOI: 10.1186/s13000-021-01172-6
Abstract: Background Many studies reporting that down-regulation of SOCS6 plays vital roles in promoting progression of malignant tumors have been published. The present study was performed to evaluate whether SOCS6 was significantly associated with prognosis of… read more here.
Keywords: analysis; expression; gist patients; socs6 ... See more keywords
BC-Box Motif in SOCS6 Induces Differentiation of Epidermal Stem Cells into GABAnergic Neurons
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DOI: 10.3390/ijms21144947
Abstract: The BC-box motif in suppressor of cytokine signaling 6 (SOCS6) promotes the neuronal differentiation of somatic stem cells, including epidermal stem cells. SOCS6 protein belongs to the group of SOCS proteins and inhibits cytokine signaling.… read more here.
Keywords: box motif; differentiation; epidermal stem; stem cells ... See more keywords