Kinetic variability in seeded formation of ALS-linked SOD1 fibrils across multiple generations.
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DOI: 10.1021/acschemneuro.9b00464
Abstract: The unseeded aggregation of superoxide dismutase-1 (SOD1) into amyloid-like fibrils occurs stochastically in vitro and in vivo, that is, isolated populations of SOD1 proteins (within microplate wells or living cells) self-assemble into amyloid at rates… read more here.
Keywords: seed; sod1; formation; sod1 fibrils ... See more keywords