Anti-SOD1 Nanobodies That Stabilize Misfolded SOD1 Proteins Also Promote Neurite Outgrowth in Mutant SOD1 Human Neurons
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DOI: 10.3390/ijms232416013
Abstract: ALS-linked mutations induce aberrant conformations within the SOD1 protein that are thought to underlie the pathogenic mechanism of SOD1-mediated ALS. Although clinical trials are underway for gene silencing of SOD1, these approaches reduce both wild-type… read more here.
Keywords: neurite outgrowth; sod1 nanobodies; anti sod1; sod1 ... See more keywords